|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3B
|
|
pubmed:dateCreated |
2005-9-14
|
|
pubmed:abstractText |
Methylentetrahydrofolate reductase plays a central role in converting folate to methyl donor for DNA methylation. Genetic variations in folate metabolism are believed to contribute to the risk of acute lymphoblastic leukemia, colon, esophageal and stomach cancer, as well as cardiovascular and cerebrovascular diseases. MTHFR C677T and A1298C polymorphisms are known to be risk factors for gastric cancer in the Chinese population. Therefore, we hypothesized that the MTHFR polymorphisms are associated with the risk of stomach cancer in Korean subjects.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0250-7005
|
|
pubmed:author |
pubmed-author:AhnJung YongJY,
pubmed-author:BoynsA RAR,
pubmed-author:ChaKwang YulKY,
pubmed-author:ChongSo YoungSY,
pubmed-author:HongSeong PyoSP,
pubmed-author:HwangSeong GyuSG,
pubmed-author:KimHyo JinHJ,
pubmed-author:KimJin KyeoungJK,
pubmed-author:KimNam KeunNK,
pubmed-author:KimSehyunS,
pubmed-author:OhDoyeunD
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
25
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2249-52
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:16158971-Adult,
pubmed-meshheading:16158971-Aged,
pubmed-meshheading:16158971-Aged, 80 and over,
pubmed-meshheading:16158971-Alleles,
pubmed-meshheading:16158971-Case-Control Studies,
pubmed-meshheading:16158971-Female,
pubmed-meshheading:16158971-Genetic Predisposition to Disease,
pubmed-meshheading:16158971-Genotype,
pubmed-meshheading:16158971-Humans,
pubmed-meshheading:16158971-Korea,
pubmed-meshheading:16158971-Male,
pubmed-meshheading:16158971-Methylenetetrahydrofolate Reductase (NADPH2),
pubmed-meshheading:16158971-Middle Aged,
pubmed-meshheading:16158971-Polymorphism, Genetic,
pubmed-meshheading:16158971-Risk Factors,
pubmed-meshheading:16158971-Stomach Neoplasms
|
|
pubmed:articleTitle |
Polymorphisms of 5,10-methylenetetrahydrofolate reductase and risk of stomach cancer in a Korean population.
|
|
pubmed:affiliation |
Institute for Clinical Research, 2Graduate School of Life Science and Biotechnology, College of Medicine, Pochon CHA University, Seongnam 463-712, South Korea.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
