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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1992-7-27
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pubmed:abstractText |
This paper describes the field evaluation of a serological test and a new in vitro assay for cell-mediated reactivity for the diagnosis of bovine tuberculosis. The use of a Mycobacterium bovis-specific antigen (MPB-70) in an ELISA to test the serological response to tuberculosis infection resulted in a specificity of 96.4% and a sensitivity of 18.1%. The most favourable results were obtained with the interferon gamma (IFN-gamma) assay which had a sensitivity of 81.8% and a specificity of 99.1%. Respective figures for the single intradermal tuberculin test were 68.1% and 96.7%. The use of MPB-70 as the antigen in the IFN-gamma assay reduced the sensitivity of this assay, without producing any useful increase in specificity. The IFN-gamma assay was also demonstrated to be a practical diagnostic test for use with large groups of cattle.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0378-1135
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
71-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:1615636-Animals,
pubmed-meshheading:1615636-Antibodies, Bacterial,
pubmed-meshheading:1615636-Antigens, Bacterial,
pubmed-meshheading:1615636-Cattle,
pubmed-meshheading:1615636-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:1615636-Evaluation Studies as Topic,
pubmed-meshheading:1615636-Immunity, Cellular,
pubmed-meshheading:1615636-Immunoenzyme Techniques,
pubmed-meshheading:1615636-Interferon-gamma,
pubmed-meshheading:1615636-Mycobacterium bovis,
pubmed-meshheading:1615636-Sensitivity and Specificity,
pubmed-meshheading:1615636-Tuberculin Test,
pubmed-meshheading:1615636-Tuberculosis, Bovine
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pubmed:year |
1992
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pubmed:articleTitle |
A field evaluation of serological and cellular diagnostic tests for bovine tuberculosis.
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pubmed:affiliation |
CSIRO, Division of Animal Health, Parkville, Vic. Australia.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|