Source:http://linkedlifedata.com/resource/pubmed/id/16148087
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2005-9-8
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pubmed:abstractText |
Appropriate control of leukocyte recruitment and activation is a fundamental requirement for competent host defense and resolving inflammation. A pivotal event that defines the successful outcome of any inflammatory event is the transition from innate to acquired immunity. In IL-6 deficiency, this process appears defective, and a series of in vivo studies have documented important roles for IL-6 in both the resolution of innate immunity and the development of acquired immune responses. Within this review, particular attention will be given to the regulatory properties of the soluble IL-6 receptor and how its activity may affect chronic disease progression.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-1767
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
175
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3463-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16148087-Chronic Disease,
pubmed-meshheading:16148087-Humans,
pubmed-meshheading:16148087-Immunity, Cellular,
pubmed-meshheading:16148087-Immunity, Innate,
pubmed-meshheading:16148087-Interleukin-6,
pubmed-meshheading:16148087-Leukocytes,
pubmed-meshheading:16148087-Receptors, Interleukin-6
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pubmed:year |
2005
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pubmed:articleTitle |
Directing transition from innate to acquired immunity: defining a role for IL-6.
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pubmed:affiliation |
Department of Medical Biochemistry and Immunology, School of Medicine, Cardiff University, Cardiff, Wales, United Kingdom.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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