Linked Life Data

16147542

Source:http://linkedlifedata.com/resource/pubmed/id/16147542

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1461
pubmed:dateCreated
2005-9-8
pubmed:abstractText
I have attempted to summarize the progress that has been made in organ transplantation in the past 50 years since the first identical twin transplant. For those who have worked long in this area its success has been remarkable. We currently expect patients to survive the operation and more than 90% of the graft to be functioning at a year with the half-life of the graft beyond 10 years, with some patients surviving into the fifth decade after kidney transplantation with grafts from unrelated donors and the fourth decade for liver transplants. Now the main stumbling block is shortage of organ donors and this is unlikely to be solved easily. There has been a considerable increase in donations from living volunteers and also the worry of immoral and illegal practices. In the future, we can expect considerable advances in immunosuppression with more effective, less toxic drugs and in some patients induction therapy that may approach tolerance so that no maintenance therapy will eventually be needed. Cell transplantation is likely to be developed as treatment for the clinic in the next 5-10 years, but developments of transplantation from animal to man still remains unsolved and unlikely to be successful in the clinic in the near future.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/16147542-10911004, http://linkedlifedata.com/resource/pubmed/commentcorrection/16147542-13099277, http://linkedlifedata.com/resource/pubmed/commentcorrection/16147542-13391513, http://linkedlifedata.com/resource/pubmed/commentcorrection/16147542-14206847, http://linkedlifedata.com/resource/pubmed/commentcorrection/16147542-15077021, http://linkedlifedata.com/resource/pubmed/commentcorrection/16147542-16147537, http://linkedlifedata.com/resource/pubmed/commentcorrection/16147542-16147538, http://linkedlifedata.com/resource/pubmed/commentcorrection/16147542-17104936, http://linkedlifedata.com/resource/pubmed/commentcorrection/16147542-1858051, http://linkedlifedata.com/resource/pubmed/commentcorrection/16147542-4894426, http://linkedlifedata.com/resource/pubmed/commentcorrection/16147542-9734890
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0962-8436
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
360
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1797-801
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Clinical transplantation: current problems, possible solutions.
pubmed:affiliation
Department of Surgery, Addenbrooke's Hospital, Cambridge, UK. cpr1000@cam.ac.uk
pubmed:publicationType
Journal Article, Review, Historical Article