Source:http://linkedlifedata.com/resource/pubmed/id/16143535
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
23
|
| pubmed:dateCreated |
2005-10-28
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| pubmed:abstractText |
Some polyphenol-containing extracts (Pelargonium sidoides, Phyllanthus amarus) and representatives of simple phenols (shikimic acid 3- and 5-O-gallate), flavan-3-ols (epigallocatechin 3-gallate), proanthocyanidins (a hexamer) and hydrolysable tannins (corilagin, casuariin, geraniin) were studied for gene expressions (iNOS, IL-1, IL-10, IL-12, IL-18, TNF-alpha, IFN-alpha/gamma) by RT-PCR. All extracts and compounds were capable of enhancing the iNOS and cytokine mRNA levels in parasitised cells when compared with those in non-infected conditions.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0968-0896
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
13
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
6470-6
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| pubmed:meshHeading |
pubmed-meshheading:16143535-Animals,
pubmed-meshheading:16143535-Cell Line,
pubmed-meshheading:16143535-Cytokines,
pubmed-meshheading:16143535-Enzyme Induction,
pubmed-meshheading:16143535-Gene Expression Regulation,
pubmed-meshheading:16143535-Leishmania major,
pubmed-meshheading:16143535-Macrophages,
pubmed-meshheading:16143535-Mice,
pubmed-meshheading:16143535-Molecular Structure,
pubmed-meshheading:16143535-Nitric Oxide Synthase,
pubmed-meshheading:16143535-Tannins
|
| pubmed:year |
2005
|
| pubmed:articleTitle |
Tannins and related compounds induce nitric oxide synthase and cytokines gene expressions in Leishmania major-infected macrophage-like RAW 264.7 cells.
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| pubmed:affiliation |
Institute of Pharmacy, Pharmaceutical Biology, Freie Universität Berlin, Germany. kolpharm@zedat.fu-berlin.de
|
| pubmed:publicationType |
Journal Article
|