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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2005-11-18
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pubmed:abstractText |
The G-308A polymorphism in the promoter region of the tumor necrosis factor alpha (TNF-alpha) gene has been reported to be associated with insulin resistance and obesity, both of which may increase the risk of diabetic nephropathy. We hypothesized that this polymorphism might interact with obesity to affect development of diabetic nephropathy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0931-0509
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2733-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16141456-Aged,
pubmed-meshheading:16141456-Alleles,
pubmed-meshheading:16141456-DNA,
pubmed-meshheading:16141456-Diabetes Mellitus, Type 2,
pubmed-meshheading:16141456-Diabetic Nephropathies,
pubmed-meshheading:16141456-Female,
pubmed-meshheading:16141456-Gene Frequency,
pubmed-meshheading:16141456-Genotype,
pubmed-meshheading:16141456-Hong Kong,
pubmed-meshheading:16141456-Humans,
pubmed-meshheading:16141456-Incidence,
pubmed-meshheading:16141456-Male,
pubmed-meshheading:16141456-Middle Aged,
pubmed-meshheading:16141456-Obesity,
pubmed-meshheading:16141456-Polymerase Chain Reaction,
pubmed-meshheading:16141456-Polymorphism, Genetic,
pubmed-meshheading:16141456-Risk Factors,
pubmed-meshheading:16141456-Tumor Necrosis Factor-alpha
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pubmed:year |
2005
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pubmed:articleTitle |
Association between tumour necrosis factor-alpha G-308A polymorphism and risk of nephropathy in obese Chinese type 2 diabetic patients.
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pubmed:affiliation |
Divison of Endocrinology, Department of Medicine & Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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