Linked Life Data

16140407

Source:http://linkedlifedata.com/resource/pubmed/id/16140407

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
2005-11-21
pubmed:abstractText
Forty-two adult Brahman-cross cattle farmed extensively in two groups, immediately adjacent to and 2 km from a vanadium processing plant respectively, were slaughtered over a 5 year period at a nearby abattoir. Cattle were being exposed to vanadium at close to no-adverse-effect levels. The dose of vanadium that cattle were taking in prior to slaughter was calculated for each animal from environmental and physiological data using a stochastic risk assessment model. The median exposure doses in the month prior to slaughter ranged from 0.55 to 2.73 mg vanadium/kg body weight/day. A range of tissues was taken from the cattle at slaughter for vanadium determination and tissue levels of vanadium in muscle, liver and kidney are reported. The concentrations of vanadium in the milk of cattle from the same farm sampled over 5 years are also reported. Concentrations were further modelled using a lognormal distribution function to look at possible extreme values that are likely to occur. The concentrations of vanadium in commonly consumed tissues ranged from <0.05 to 11.51 mg/kg (wet-mass basis). The median concentration of vanadium in milk was 0.23 mg vanadium/kg. People drinking milk were at highest risk. The potential oral daily intake of vanadium for people consuming these foodstuffs was modelled using a stochastic model. The model predicted that there is less than a 5% chance that the potential daily intake of vanadium from milk will be >0.44 microg/kg/day for adults. Based on this upper limit it was concluded from current knowledge of toxicity in humans that the tissue and milk residues from cattle should pose no health risk to the consumer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0167-5877
pubmed:author
pubmed:issnType
Print
pubmed:day
12
pubmed:volume
72
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
281-90
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
The public health implications of farming cattle in areas with high background concentrations of vanadium.
pubmed:affiliation
Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, Gauteng 0110, South Africa. bgummow@op.up.ac.za
pubmed:publicationType
Journal Article