Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
22
pubmed:dateCreated
2005-9-6
pubmed:abstractText
4-Hydroxynonenal (4HNE), generated during polyunsaturated fatty acid oxidation, is present in atherosclerotic lesions. As 4HNE is able to react with phosphatidylethanolamine (PE), we investigated, using AC polarography, whether it may alter the physico-chemical state of a condensed PE-containing phospholipid monolayer and its interaction with apoA-I. The stability of a phospholipid monolayer relative to potential (around the potential of zero charge) is dependent on lipid composition (PE>PC>PE/PC). ApoA-I insertion into PE/PC monolayer is easier than in PC monolayer. Pre-treatment of PE/PC monolayer by 4HNE does not alter monolayer stability, but decreases apo A-I insertion into the monolayer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0014-5793
pubmed:author
pubmed:issnType
Print
pubmed:day
12
pubmed:volume
579
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5074-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Effect of 4-hydroxynonenal on phosphatidylethanolamine containing condensed monolayer and on its interaction with apolipoprotein A-I.
pubmed:affiliation
INSERM U-466, Biochemistry Department, IFR31, CHU Rangueil 1 Avenue Jean Poulhés, TSA 50032-31059, Toulouse Cedex 9, France. lecompte@cict.fr
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't