Source:http://linkedlifedata.com/resource/pubmed/id/16137166
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5-6
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pubmed:dateCreated |
2005-9-2
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pubmed:abstractText |
This study retrospectively examines the spectrum of sacrococcygeal tumors reported in a tertiary paediatric pathology department during a 15-year period. There were 85 sacrococcygeal tumors identified in total, including 79 (93%) sacrococcygeal germ cell tumors, of which 62 (78%) were benign, whereas 17 (22%) contained malignant yolk sac tumor elements. The median age at examination in cases with malignant elements present was significantly greater than in those with benign sacrococcygeal teratoma only (median 2 years, range birth--3 years versus median 1 week, range birth--10 years, respectively; p < .01). Of the 85 cases of total sacrococcygeal lesions 6 (7%) represented pathologies other than sacrococcygeal teratoma, including one case each of neuroblastoma, ganglioneuroma, myxopapillary ependymoma, primitive neuroectodermal tumor, lipomatous tumor, and unclassifiable inflammatory tumor. Of these 6 cases 3 were malignant (50%) compared with 17 of the 79 cases of sacrococcygeal germ cell tumors (22%; Z =1.59, p = .08). The median age in the group of non-germ-cell sacrococcygeal masses was 3 years (range 5 months to 13 years).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1551-3815
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
295-303
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pubmed:dateRevised |
2008-10-1
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pubmed:meshHeading |
pubmed-meshheading:16137166-Adolescent,
pubmed-meshheading:16137166-Age Factors,
pubmed-meshheading:16137166-Child,
pubmed-meshheading:16137166-Child, Preschool,
pubmed-meshheading:16137166-Endodermal Sinus Tumor,
pubmed-meshheading:16137166-Ependymoma,
pubmed-meshheading:16137166-Female,
pubmed-meshheading:16137166-Humans,
pubmed-meshheading:16137166-Infant,
pubmed-meshheading:16137166-Infant, Newborn,
pubmed-meshheading:16137166-Male,
pubmed-meshheading:16137166-Neoplasms, Germ Cell and Embryonal,
pubmed-meshheading:16137166-Retrospective Studies,
pubmed-meshheading:16137166-Sacrococcygeal Region,
pubmed-meshheading:16137166-Teratoma,
pubmed-meshheading:16137166-Time Factors
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pubmed:articleTitle |
Sacrococcygeal tumors in infancy and childhood; a retrospective histopathological review of 85 cases.
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pubmed:affiliation |
Department of Histopathology, Camelia Botnar Laboratories, Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK. SebirN@gosh.nhs.uk
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pubmed:publicationType |
Journal Article,
Review
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