|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2005-9-1
|
|
pubmed:abstractText |
Clinical and laboratory studies suggest that lidocaine is more neurotoxic than bupivacaine. However, histological evidence of their comparative neurotoxicity is sparse. We thus pathologically and functionally compared the intrathecal neurotoxicity of these agents.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1098-7339
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
30
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
464-72
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:16135351-Anesthesia Recovery Period,
pubmed-meshheading:16135351-Anesthetics, Local,
pubmed-meshheading:16135351-Animals,
pubmed-meshheading:16135351-Bupivacaine,
pubmed-meshheading:16135351-Cauda Equina,
pubmed-meshheading:16135351-Dose-Response Relationship, Drug,
pubmed-meshheading:16135351-Glucose Solution, Hypertonic,
pubmed-meshheading:16135351-Hydrogen-Ion Concentration,
pubmed-meshheading:16135351-Injections, Spinal,
pubmed-meshheading:16135351-Lidocaine,
pubmed-meshheading:16135351-Male,
pubmed-meshheading:16135351-Microscopy, Electron,
pubmed-meshheading:16135351-Microscopy, Polarization,
pubmed-meshheading:16135351-Motor Activity,
pubmed-meshheading:16135351-Neurotoxicity Syndromes,
pubmed-meshheading:16135351-Osmolar Concentration,
pubmed-meshheading:16135351-Rats,
pubmed-meshheading:16135351-Rats, Wistar,
pubmed-meshheading:16135351-Sensory Thresholds,
pubmed-meshheading:16135351-Spinal Cord,
pubmed-meshheading:16135351-Spinal Nerve Roots,
pubmed-meshheading:16135351-Time Factors
|
|
pubmed:articleTitle |
Neurotoxicity of intrathecally administered bupivacaine involves the posterior roots/posterior white matter and is milder than lidocaine in rats.
|
|
pubmed:affiliation |
Department of Anesthesiology, Kitasato University School of Medicine, 1-15-1 Kitasdato, Sagamihara, Kanagawa 228-8555, Japan. takenami@med.kitasato-u.ac.jp
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
