Very few chemical enhancers for transdermal drug delivery have been approved for clinical use due to irritancy and toxicity concerns. Novel chemical enhancers (iminosulfuranes) were synthesized and studied for their activity and toxicity.
Laboratory for Drug Delivery, Department of Pharmacology and Physiology, University of Medicine and Dentistry of New Jersey, NJMS, 111 Lock Street, Newark, NJ 07103, USA. yifan.song@spcorp.com