Source:http://linkedlifedata.com/resource/pubmed/id/16132284
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
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| pubmed:dateCreated |
2006-1-19
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| pubmed:abstractText |
The aim of this study was to evaluate the ability to recover from exercise in patients with a Mustard/Senning (M/S) repair for transposition of the great arteries and to identify the major determinants. A total of 40 consecutive patients with a M/S repair at a mean age of 10.0 +/- 9.8 months underwent maximal cardiopulmonary exercise testing at 19.5 +/- 11.3 years of age. Results were compared to those of a cohort of 153 healthy individuals. Decay of oxygen uptake (VO2), CO2 (VCO2), minute ventilation (VE), heart rate (HR) was calculated for the first minute of recovery. M/S patients had reduced peak VO2(22.9 +/- 7.2 vs 34.2 +/- 9.5 ml O2/kg/min, p < 0.0001) and VO2 slope (0.27 +/- 0.10 vs 0.47 +/- 0.2 L O2/min, p < 0.0001), Peak O2 pulse (p < 0.0001) and peak HR (p = 0.001) were reduced. VCO2 and VE slopes were reduced (p < 0.0001 for both), whereas HR slope was similar (p = 0.38). In M/S patients, the only independent determinants of VO2 slope during recovery were pulse O2 slope (p < 0.0001) and VCO2 slope (p < 0.0001). In M/S patients, a limited cardiopulmonary reserve affects not only maximal exercise responses but also the recovery phase. A prolonged recovery of O2 pulse and a prolonged CO2 retention with subsequent prolonged hyperpnea are the main determinants of the delayed recovery.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:issn |
0172-0643
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
26
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
821-6
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| pubmed:dateRevised |
2008-2-20
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| pubmed:meshHeading |
pubmed-meshheading:16132284-Adolescent,
pubmed-meshheading:16132284-Adult,
pubmed-meshheading:16132284-Cardiac Surgical Procedures,
pubmed-meshheading:16132284-Child,
pubmed-meshheading:16132284-Exercise Test,
pubmed-meshheading:16132284-Exercise Tolerance,
pubmed-meshheading:16132284-Female,
pubmed-meshheading:16132284-Heart Rate,
pubmed-meshheading:16132284-Humans,
pubmed-meshheading:16132284-Male,
pubmed-meshheading:16132284-Oxygen Consumption,
pubmed-meshheading:16132284-Postoperative Period,
pubmed-meshheading:16132284-Time Factors,
pubmed-meshheading:16132284-Transposition of Great Vessels
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| pubmed:articleTitle |
Recovery kinetics of oxygen uptake is abnormally prolonged in patients with Mustard/Senning repair for transposition of the great arteries.
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| pubmed:affiliation |
Pediatric Cardiology and Adult Congenital Unit, University of Bologna, Via Massarenti 9, Bologna, 40138, Italy. alessandro5574@iol.it
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| pubmed:publicationType |
Journal Article
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