Source:http://linkedlifedata.com/resource/pubmed/id/16128595
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2005-8-30
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pubmed:abstractText |
To investigate the bioavailability and bioequivalence of three different formulations of eslicarbazepine acetate (BIA 2-093): 50 mg/mL oral suspension (test 1), 200mg tablets (test 2) and 800mg tablets (reference). DESIGN, SUBJECTS AND METHODS: Single-centre, open-label, randomised, three-way crossover study in 18 healthy subjects. The study consisted of three consecutive periods separated by a washout period of 7 days or more. Each subject received a single dose of eslicarbazepine acetate 800mg on three different occasions: 16mL of oral 50 mg/mL suspension, four 200mg tablets or one 800mg tablet.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1174-5886
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
253-60
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16128595-Administration, Oral,
pubmed-meshheading:16128595-Adolescent,
pubmed-meshheading:16128595-Adult,
pubmed-meshheading:16128595-Biological Availability,
pubmed-meshheading:16128595-Cross-Over Studies,
pubmed-meshheading:16128595-Dibenzazepines,
pubmed-meshheading:16128595-Dose-Response Relationship, Drug,
pubmed-meshheading:16128595-Female,
pubmed-meshheading:16128595-Humans,
pubmed-meshheading:16128595-Male,
pubmed-meshheading:16128595-Middle Aged,
pubmed-meshheading:16128595-Suspensions,
pubmed-meshheading:16128595-Tablets,
pubmed-meshheading:16128595-Therapeutic Equivalency
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pubmed:year |
2005
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pubmed:articleTitle |
Eslicarbazepine acetate (BIA 2-093) : relative bioavailability and bioequivalence of 50 mg/mL oral suspension and 200mg and 800mg tablet formulations.
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pubmed:affiliation |
CEB - Centre for Bioavailability Studies, Coimbra, Portugal.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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