Source:http://linkedlifedata.com/resource/pubmed/id/16127933
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
16
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pubmed:dateCreated |
2005-8-30
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pubmed:abstractText |
We describe a novel microscopy technique for quantitative phase-contrast imaging of a transparent specimen. The technique is based on depth-resolved phase information provided by common path spectral-domain optical coherence tomography and can measure minute phase variations caused by changes in refractive index and thickness inside the specimen. We demonstrate subnanometer level path-length sensitivity and present images obtained on reflection from a known phase object and human epithelial cheek cells.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0146-9592
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2131-3
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16127933-Cells, Cultured,
pubmed-meshheading:16127933-Epithelial Cells,
pubmed-meshheading:16127933-Equipment Design,
pubmed-meshheading:16127933-Equipment Failure Analysis,
pubmed-meshheading:16127933-Humans,
pubmed-meshheading:16127933-Image Enhancement,
pubmed-meshheading:16127933-Imaging, Three-Dimensional,
pubmed-meshheading:16127933-Microscopy, Phase-Contrast,
pubmed-meshheading:16127933-Reproducibility of Results,
pubmed-meshheading:16127933-Sensitivity and Specificity,
pubmed-meshheading:16127933-Spectrum Analysis,
pubmed-meshheading:16127933-Tomography, Optical Coherence
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pubmed:year |
2005
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pubmed:articleTitle |
Spectral-domain optical coherence phase microscopy for quantitative phase-contrast imaging.
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pubmed:affiliation |
Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. cmjoo@mit.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Evaluation Studies,
Research Support, N.I.H., Extramural
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