|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
9
|
|
pubmed:dateCreated |
2005-8-29
|
|
pubmed:abstractText |
We conducted a prevalence study of mutations in Plasmodium falciparum that are associated with antifolate resistance in Blantyre, Malawi. The dihydrofolate reductase 164-Leu mutation, which confers resistance to both pyrimethamine and chlorproguanil, was found in 4.7% of the samples. Previously unreported mutations in dihydropteroate synthase were also found.
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/16127071-11044269,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16127071-11807721,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16127071-12201581,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16127071-12387962,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16127071-12630380,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16127071-12659974,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16127071-12792863,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16127071-12950663,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16127071-15096809,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16127071-15117308,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16127071-15183616,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16127071-15183620,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16127071-15273102,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16127071-15589802,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16127071-2183221,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16127071-9395372
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0066-4804
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
49
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
3919-21
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:16127071-Animals,
pubmed-meshheading:16127071-Antimalarials,
pubmed-meshheading:16127071-DNA Primers,
pubmed-meshheading:16127071-Drug Combinations,
pubmed-meshheading:16127071-Drug Resistance,
pubmed-meshheading:16127071-Folic Acid Antagonists,
pubmed-meshheading:16127071-Humans,
pubmed-meshheading:16127071-Malaria, Falciparum,
pubmed-meshheading:16127071-Malawi,
pubmed-meshheading:16127071-Mutation,
pubmed-meshheading:16127071-Plasmodium falciparum,
pubmed-meshheading:16127071-Proguanil,
pubmed-meshheading:16127071-Pyrimethamine,
pubmed-meshheading:16127071-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16127071-Sulfadoxine,
pubmed-meshheading:16127071-Tetrahydrofolate Dehydrogenase
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
Mutations associated with sulfadoxine-pyrimethamine and chlorproguanil resistance in Plasmodium falciparum isolates from Blantyre, Malawi.
|
|
pubmed:affiliation |
Department of Epidemiology, University of North Carolina School of Public Health, Chapel Hill, NC 27599-7435, USA. alker@unc.edu
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, N.I.H., Extramural
|
