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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2005-11-25
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pubmed:abstractText |
A reduced number of progressively motile sperm (as may occur in cases of asthenozoospermia or when cryopreserved spermatozoa are used for fertilization) limits the possibility of applying various assisted reproductive techniques (ARTs). We previously showed that incubation of sperm with the phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 increases sperm progressive motility and enhances the number of sperm recovered by capacitation protocols used in ART.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0268-1161
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3500-4
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:16126754-Animals,
pubmed-meshheading:16126754-Blastocyst,
pubmed-meshheading:16126754-Blotting, Western,
pubmed-meshheading:16126754-Chromones,
pubmed-meshheading:16126754-Cryopreservation,
pubmed-meshheading:16126754-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:16126754-Embryo, Mammalian,
pubmed-meshheading:16126754-Embryonic Development,
pubmed-meshheading:16126754-Enzyme Inhibitors,
pubmed-meshheading:16126754-Epididymis,
pubmed-meshheading:16126754-Female,
pubmed-meshheading:16126754-Fertilization,
pubmed-meshheading:16126754-Humans,
pubmed-meshheading:16126754-Ice,
pubmed-meshheading:16126754-Male,
pubmed-meshheading:16126754-Mice,
pubmed-meshheading:16126754-Morpholines,
pubmed-meshheading:16126754-Oocytes,
pubmed-meshheading:16126754-Phosphatidylinositol 3-Kinases,
pubmed-meshheading:16126754-Phosphorylation,
pubmed-meshheading:16126754-Sperm Capacitation,
pubmed-meshheading:16126754-Sperm Motility,
pubmed-meshheading:16126754-Spermatozoa,
pubmed-meshheading:16126754-Time Factors
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pubmed:year |
2005
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pubmed:articleTitle |
Enhancement of mouse sperm motility by the PI3-kinase inhibitor LY294002 does not result in toxic effects on preimplantation embryo development.
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pubmed:affiliation |
Department of Clinical Physiopathology, Center of Research, Transfer and High Education, DENOthe Andrology Unit, University of Florence, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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