| pubmed-article:16125151 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16125151 | lifeskim:mentions | umls-concept:C0030193 | lld:lifeskim |
| pubmed-article:16125151 | lifeskim:mentions | umls-concept:C0060993 | lld:lifeskim |
| pubmed-article:16125151 | lifeskim:mentions | umls-concept:C0442805 | lld:lifeskim |
| pubmed-article:16125151 | lifeskim:mentions | umls-concept:C0205178 | lld:lifeskim |
| pubmed-article:16125151 | lifeskim:mentions | umls-concept:C0333348 | lld:lifeskim |
| pubmed-article:16125151 | lifeskim:mentions | umls-concept:C0205100 | lld:lifeskim |
| pubmed-article:16125151 | lifeskim:mentions | umls-concept:C0441712 | lld:lifeskim |
| pubmed-article:16125151 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:16125151 | pubmed:dateCreated | 2005-9-5 | lld:pubmed |
| pubmed-article:16125151 | pubmed:abstractText | Galanin (GAL) is a neuropeptide involved in pain transmission. Intraplantar GAL at low doses enhances capsaicin (CAP)-induced pain behaviors in rat, suggesting an excitatory role for GAL under acute inflammatory conditions. The mechanisms underlying this pro-nociceptive action have not yet been elucidated. Thus, the present study investigated the role of protein kinase C (PKC) in the GAL enhancement of CAP-induced inflammatory pain. Ipsilateral, but not contralateral, calphostin C, a PKC inhibitor, blocked GAL-induced potentiation of CAP-evoked inflammatory pain in a dose-dependent fashion. Peripheral activation of PKC using the phorbol ester phorbol-12-myristate-13-acetate (PMA) mimicked the pro-nociceptive effect of GAL. These results suggest that GAL enhances acute inflammatory pain through activation of PKC intracellular pathways. | lld:pubmed |
| pubmed-article:16125151 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16125151 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16125151 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16125151 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16125151 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16125151 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16125151 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16125151 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16125151 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16125151 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16125151 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16125151 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16125151 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16125151 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:16125151 | pubmed:issn | 0006-8993 | lld:pubmed |
| pubmed-article:16125151 | pubmed:author | pubmed-author:CarltonSusan... | lld:pubmed |
| pubmed-article:16125151 | pubmed:author | pubmed-author:Jimenez-Andra... | lld:pubmed |
| pubmed-article:16125151 | pubmed:author | pubmed-author:ZhouShengtaiS | lld:pubmed |
| pubmed-article:16125151 | pubmed:author | pubmed-author:YamaniAmmarA | lld:pubmed |
| pubmed-article:16125151 | pubmed:author | pubmed-author:Castañeda-Her... | lld:pubmed |
| pubmed-article:16125151 | pubmed:author | pubmed-author:Valencia de... | lld:pubmed |
| pubmed-article:16125151 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16125151 | pubmed:day | 21 | lld:pubmed |
| pubmed-article:16125151 | pubmed:volume | 1056 | lld:pubmed |
| pubmed-article:16125151 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16125151 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16125151 | pubmed:pagination | 113-7 | lld:pubmed |
| pubmed-article:16125151 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:meshHeading | pubmed-meshheading:16125151... | lld:pubmed |
| pubmed-article:16125151 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16125151 | pubmed:articleTitle | Mechanism by which peripheral galanin increases acute inflammatory pain. | lld:pubmed |
| pubmed-article:16125151 | pubmed:affiliation | Seccion Externa de Farmacologia, Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional, Mexico, D.F., Mexico. | lld:pubmed |
| pubmed-article:16125151 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16125151 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:16125151 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:16125151 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:16125151 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16125151 | lld:pubmed |
