Source:http://linkedlifedata.com/resource/pubmed/id/16124773
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2005-8-29
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pubmed:abstractText |
Bioactivity-guided fractionation of an ethanol extract of the aerial parts of Dioscorea opposita afforded a new compound, 6,7-dihydroxy-2-methoxy-1,4-phenanthrenedione (1), and four known compounds, chrysoeriol 4'-O-beta-D-glucopyranoside (2), chrysoeriol 7-O-beta-D-glucopyranoside (3), alternanthin (4), and daucosterol. The structure of 1 was established on the basis of the interpretation of its 1D and 2D NMR spectrascopic data. Compounds 1-4 exhibited both promising neuroprotective effects and discernible to moderate antioxidant activities in vitro.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0163-3864
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1259-61
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16124773-Antioxidants,
pubmed-meshheading:16124773-Dioscorea,
pubmed-meshheading:16124773-Drugs, Chinese Herbal,
pubmed-meshheading:16124773-Molecular Structure,
pubmed-meshheading:16124773-Neuroprotective Agents,
pubmed-meshheading:16124773-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:16124773-Phenanthrenes,
pubmed-meshheading:16124773-Plants, Medicinal
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pubmed:year |
2005
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pubmed:articleTitle |
Neuroprotective and antioxidant activity of compounds from the aerial parts of Dioscorea opposita.
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pubmed:affiliation |
Laboratory of Pharmaceutical Sciences, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, People's Republic of China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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