Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2005-8-26
pubmed:abstractText
Oxidative stress has been implicated in a variety of diseases of the eye. In several other tissues, keratinocyte growth factor (KGF) has been shown to prevent negative cellular changes associated with oxidative insult, such as permeability increases and nuclear DNA damage. In this study, we looked at whether KGF provided these same protective effects to cultured human retinal pigmented epithelial (RPE) cells (ARPE-19).
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Actins, http://linkedlifedata.com/resource/pubmed/chemical/FGF7 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/FGFR2 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factor 7, http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factors, http://linkedlifedata.com/resource/pubmed/chemical/Hydrogen Peroxide, http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 1, http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 3, http://linkedlifedata.com/resource/pubmed/chemical/Oxidants, http://linkedlifedata.com/resource/pubmed/chemical/Oxygen, http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Fibroblast Growth..., http://linkedlifedata.com/resource/pubmed/chemical/Receptor Protein-Tyrosine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Fibroblast Growth Factor, http://linkedlifedata.com/resource/pubmed/chemical/keratinocyte growth factor receptor
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0146-0404
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3435-42
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:16123449-Actins, pubmed-meshheading:16123449-Blotting, Western, pubmed-meshheading:16123449-Cell Proliferation, pubmed-meshheading:16123449-Cell Survival, pubmed-meshheading:16123449-Cells, Cultured, pubmed-meshheading:16123449-DNA Damage, pubmed-meshheading:16123449-Fibroblast Growth Factor 7, pubmed-meshheading:16123449-Fibroblast Growth Factors, pubmed-meshheading:16123449-Humans, pubmed-meshheading:16123449-Hydrogen Peroxide, pubmed-meshheading:16123449-Mitogen-Activated Protein Kinase 1, pubmed-meshheading:16123449-Mitogen-Activated Protein Kinase 3, pubmed-meshheading:16123449-Oxidants, pubmed-meshheading:16123449-Oxidative Stress, pubmed-meshheading:16123449-Oxygen, pubmed-meshheading:16123449-Permeability, pubmed-meshheading:16123449-Pigment Epithelium of Eye, pubmed-meshheading:16123449-Receptor, Fibroblast Growth Factor, Type 2, pubmed-meshheading:16123449-Receptor Protein-Tyrosine Kinases, pubmed-meshheading:16123449-Receptors, Fibroblast Growth Factor, pubmed-meshheading:16123449-Reverse Transcriptase Polymerase Chain Reaction
pubmed:year
2005
pubmed:articleTitle
KGF prevents oxygen-mediated damage in ARPE-19 cells.
pubmed:affiliation
Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208-3107, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural