Source:http://linkedlifedata.com/resource/pubmed/id/16122739
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
22
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pubmed:dateCreated |
2005-9-6
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pubmed:abstractText |
Functionally sterile honey bee workers synthesize the yolk protein vitellogenin while performing nest tasks. The subsequent shift to foraging is linked to a reduced vitellogenin and an increased juvenile hormone (JH) titer. JH is a principal controller of vitellogenin expression and behavioral development. Yet, we show here that silencing of vitellogenin expression causes a significant increase in JH titer and its putative receptor. Mathematically, the increase corresponds to a dynamic dose-response. This role of vitellogenin in the tuning of the endocrine system is uncommon and may elucidate how an ancestral pathway of fertility regulation has been remodeled into a novel circuit controlling social behavior.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0014-5793
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
12
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pubmed:volume |
579
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4961-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16122739-Animals,
pubmed-meshheading:16122739-Bees,
pubmed-meshheading:16122739-Behavior, Animal,
pubmed-meshheading:16122739-Female,
pubmed-meshheading:16122739-Gene Silencing,
pubmed-meshheading:16122739-Juvenile Hormones,
pubmed-meshheading:16122739-Phenotype,
pubmed-meshheading:16122739-RNA Interference,
pubmed-meshheading:16122739-Vitellogenins
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pubmed:year |
2005
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pubmed:articleTitle |
Vitellogenin regulates hormonal dynamics in the worker caste of a eusocial insect.
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pubmed:affiliation |
Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Brazil.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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