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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2005-9-19
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pubmed:abstractText |
The protective role of high-density lipoprotein (HDL) in the cardiovascular system is related to its role in the reverse transport of cholesterol from the arterial wall to the liver for subsequent excretion via the bile. Scavenger receptor class B type I (SR-BI) binds HDL and mediates selective uptake of cholesterol ester and cellular efflux of cholesterol to HDL. The role of SR-BI in atherosclerosis has been well established in murine models but it remains unclear whether SR-BI plays an equally important role in atherosclerosis in humans. The aim of this study was to investigate the expression of SR-BI and its isoforms in human macrophages and atherosclerotic plaques.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/16122381-10195911,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16122381-10397692,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16122381-10400916,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16122381-10430941,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16122381-10614769,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/16122381-10829064,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/16122381-11874431,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/16122381-9891004
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/Lysosome-Associated Membrane...,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Isoforms,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Scavenger,
http://linkedlifedata.com/resource/pubmed/chemical/SCARB1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/SCARB2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Scavenger Receptors, Class B,
http://linkedlifedata.com/resource/pubmed/chemical/Sialoglycoproteins
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2261
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pubmed:author |
pubmed-author:CarlssonBjörnB,
pubmed-author:CarlssonLena M SLM,
pubmed-author:EnglundMikael C OMC,
pubmed-author:FagerbergBjörnB,
pubmed-author:HäggDaniel ADA,
pubmed-author:Mattsson-HultenLillemorL,
pubmed-author:OhlssonBertil GBG,
pubmed-author:SnäckestrandMagnus S CMS,
pubmed-author:StemmeVeronikaV,
pubmed-author:SvenssonPer-ArnePA,
pubmed-author:ThelleDag SDS,
pubmed-author:WiklundOlovO
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
25
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:16122381-Adult,
pubmed-meshheading:16122381-Alternative Splicing,
pubmed-meshheading:16122381-Amino Acid Motifs,
pubmed-meshheading:16122381-Amino Acid Sequence,
pubmed-meshheading:16122381-Atherosclerosis,
pubmed-meshheading:16122381-Base Sequence,
pubmed-meshheading:16122381-Cell Hypoxia,
pubmed-meshheading:16122381-Cells, Cultured,
pubmed-meshheading:16122381-Female,
pubmed-meshheading:16122381-Gene Expression Regulation,
pubmed-meshheading:16122381-Humans,
pubmed-meshheading:16122381-Lipoproteins, LDL,
pubmed-meshheading:16122381-Lysosome-Associated Membrane Glycoproteins,
pubmed-meshheading:16122381-Macrophages,
pubmed-meshheading:16122381-Male,
pubmed-meshheading:16122381-Molecular Sequence Data,
pubmed-meshheading:16122381-Protein Isoforms,
pubmed-meshheading:16122381-RNA, Messenger,
pubmed-meshheading:16122381-Receptors, Scavenger,
pubmed-meshheading:16122381-Scavenger Receptors, Class B,
pubmed-meshheading:16122381-Sialoglycoproteins,
pubmed-meshheading:16122381-src Homology Domains
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pubmed:year |
2005
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