Linked Life Data

16121688

Source:http://linkedlifedata.com/resource/pubmed/id/16121688

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2005-8-26
pubmed:abstractText
Nucleoside/nucleotide analogs (NAs) are essential components of most current antiretroviral regimens. Although many dual NA combinations may be used as backbones, not all display optimal results. For instance, some associations should be avoided due to antagonism (eg, zidovudine plus stavudine), high rates of toxicity (eg, didanosine plus stavudine) and/or increased risk of virological failure (eg, didanosine plus tenofovir). Moreover, the knowledge of plasma and intracellular interactions between different NAs is important for choosing appropriate combinations and optimal doses in order to optimize antiviral efficacy and minimize toxicities.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1472-4472
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
812-22
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Nucleoside/nucleotide backbones for the treatment of HIV infection.
pubmed:affiliation
Service of Infectious Diseases and Service of Pharmacy, Hospital Carlos III, Madrid 28029, Spain.
pubmed:publicationType
Journal Article, Review