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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2005-8-25
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pubmed:abstractText |
Caveolin-1 is the principal protein that composes caveolae, which are vesicular invaginations present on the plasma membrane of different cell types. Caveolae are involved in a variety of cellular functions including regulation of proliferation rate and resistance to chemotherapeutic drugs. Chemotherapy frequently induces alopecia which is reversible most probably due to the low proliferative rate of hair follicle stem cells and due to the expression of proteins which confer resistance.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers,
http://linkedlifedata.com/resource/pubmed/chemical/Catnb protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Cav1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Caveolin 1,
http://linkedlifedata.com/resource/pubmed/chemical/Caveolins,
http://linkedlifedata.com/resource/pubmed/chemical/Cytoskeletal Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Doxorubicin,
http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators,
http://linkedlifedata.com/resource/pubmed/chemical/beta Catenin
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0007-0963
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
153
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
506-13
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16120134-Alopecia,
pubmed-meshheading:16120134-Animals,
pubmed-meshheading:16120134-Antineoplastic Agents,
pubmed-meshheading:16120134-Biological Markers,
pubmed-meshheading:16120134-Caveolin 1,
pubmed-meshheading:16120134-Caveolins,
pubmed-meshheading:16120134-Cell Proliferation,
pubmed-meshheading:16120134-Cytoskeletal Proteins,
pubmed-meshheading:16120134-Doxorubicin,
pubmed-meshheading:16120134-Drug Resistance,
pubmed-meshheading:16120134-Hair Follicle,
pubmed-meshheading:16120134-Hair Removal,
pubmed-meshheading:16120134-Immunohistochemistry,
pubmed-meshheading:16120134-Mice,
pubmed-meshheading:16120134-Mice, Inbred C57BL,
pubmed-meshheading:16120134-Models, Animal,
pubmed-meshheading:16120134-Multipotent Stem Cells,
pubmed-meshheading:16120134-Trans-Activators,
pubmed-meshheading:16120134-beta Catenin
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pubmed:year |
2005
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pubmed:articleTitle |
Caveolin-1 is expressed on multipotent cells of hair follicles and might be involved in their resistance to chemotherapy.
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pubmed:affiliation |
Department of Human Morphology, National Cancer Institute, Università degli Studi di Milano, Via Mangiagalli, 31, 20133 Milan, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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