Linked Life Data

16119839

Source:http://linkedlifedata.com/resource/pubmed/id/16119839

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2005-8-25
pubmed:abstractText
We report a 24-year-old man with severe methanol intoxication, who showed cerebral and optic nerve damages on MRI. He was admitted to our hospital with an acute onset of unconsciousness and severe metabolic acidosis, and was immediately treated by hemodialysis. His serum methanol concentration was 261.5 mg/dl. Although this methanol concentration was lethal, he was rescued by intensive care. Three days after admission, brain MRI was performed. Diffusion weighted images showed abnormal hyperintensities in bilateral putamina, subcortical white matter and cerebellar hemispheres. STIR sequence revealed bilateral optic nerve swelling with irregular hyperintense rims. These MRI features might reflect the optic nerve damages, mainly demyelination of the optic nerves caused by a myelinoclastic effect of formic acid, a metabolite of methanol.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0009-918X
pubmed:author
pubmed:issnType
Print
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
527-30
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
[A case of methanol intoxication with optic neuropathy visualized on STIR sequence of MR images].
pubmed:affiliation
Department of Neurology, Hematology, Metabolism, Endocrinology and Diabetes, Yamagata University School of Medicine.
pubmed:publicationType
Journal Article, English Abstract, Case Reports