| pubmed-article:16119242 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16119242 | lifeskim:mentions | umls-concept:C0012984 | lld:lifeskim |
| pubmed-article:16119242 | lifeskim:mentions | umls-concept:C0027740 | lld:lifeskim |
| pubmed-article:16119242 | lifeskim:mentions | umls-concept:C0020614 | lld:lifeskim |
| pubmed-article:16119242 | lifeskim:mentions | umls-concept:C0013812 | lld:lifeskim |
| pubmed-article:16119242 | lifeskim:mentions | umls-concept:C2698172 | lld:lifeskim |
| pubmed-article:16119242 | lifeskim:mentions | umls-concept:C1708533 | lld:lifeskim |
| pubmed-article:16119242 | lifeskim:mentions | umls-concept:C2003851 | lld:lifeskim |
| pubmed-article:16119242 | lifeskim:mentions | umls-concept:C0205324 | lld:lifeskim |
| pubmed-article:16119242 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:16119242 | pubmed:dateCreated | 2005-8-25 | lld:pubmed |
| pubmed-article:16119242 | pubmed:abstractText | A flat-interface nerve electrode (FINE) is presented as a potential solution for using multifascicle nerve recordings as part of a closed-loop control system. To investigate the ability of this electrode to achieve selective recordings at physiological signal-to-noise ratio (SNR), a finite-element model (FEM) of a beagle hypoglossal nerve with an implanted FINE was constructed. Action potentials (AP) were generated at various SNR levels and the performance of the electrode was assessed with a selectivity index (0 < or = SI < or = 1; ability of the electrode to distinguish two active sources). Computer simulations yielded a selective range (0.05 < or = SI < or = 0.76) that was 1) related to the interfiber distance and 2) used to predict the minimum interfiber distance (0.23 mm < or = d < or = 1.42 mm) for selective recording at each SNR. The SI was further evaluated using recorded compound APs elicited from electrically activating the branches of the beagle hypoglossal nerve. For all experiments (n = 7), the selectivity (SI = 0.45 +/- 0.16) was within the range predicted by the FEM. This study suggests that the FINE can record the activity from a multifasciculated nerve and, more importantly, distinguish neural signals from pairs of fascicles at physiologic SNR. | lld:pubmed |
| pubmed-article:16119242 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16119242 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16119242 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16119242 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16119242 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16119242 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:16119242 | pubmed:issn | 0018-9294 | lld:pubmed |
| pubmed-article:16119242 | pubmed:author | pubmed-author:DurandDominiq... | lld:pubmed |
| pubmed-article:16119242 | pubmed:author | pubmed-author:YooPaul BPB | lld:pubmed |
| pubmed-article:16119242 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16119242 | pubmed:volume | 52 | lld:pubmed |
| pubmed-article:16119242 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16119242 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16119242 | pubmed:pagination | 1461-9 | lld:pubmed |
| pubmed-article:16119242 | pubmed:dateRevised | 2009-11-11 | lld:pubmed |
| pubmed-article:16119242 | pubmed:meshHeading | pubmed-meshheading:16119242... | lld:pubmed |
| pubmed-article:16119242 | pubmed:meshHeading | pubmed-meshheading:16119242... | lld:pubmed |
| pubmed-article:16119242 | pubmed:meshHeading | pubmed-meshheading:16119242... | lld:pubmed |
| pubmed-article:16119242 | pubmed:meshHeading | pubmed-meshheading:16119242... | lld:pubmed |
| pubmed-article:16119242 | pubmed:meshHeading | pubmed-meshheading:16119242... | lld:pubmed |
| pubmed-article:16119242 | pubmed:meshHeading | pubmed-meshheading:16119242... | lld:pubmed |
| pubmed-article:16119242 | pubmed:meshHeading | pubmed-meshheading:16119242... | lld:pubmed |
| pubmed-article:16119242 | pubmed:meshHeading | pubmed-meshheading:16119242... | lld:pubmed |
| pubmed-article:16119242 | pubmed:meshHeading | pubmed-meshheading:16119242... | lld:pubmed |
| pubmed-article:16119242 | pubmed:meshHeading | pubmed-meshheading:16119242... | lld:pubmed |
| pubmed-article:16119242 | pubmed:meshHeading | pubmed-meshheading:16119242... | lld:pubmed |
| pubmed-article:16119242 | pubmed:meshHeading | pubmed-meshheading:16119242... | lld:pubmed |
| pubmed-article:16119242 | pubmed:meshHeading | pubmed-meshheading:16119242... | lld:pubmed |
| pubmed-article:16119242 | pubmed:meshHeading | pubmed-meshheading:16119242... | lld:pubmed |
| pubmed-article:16119242 | pubmed:meshHeading | pubmed-meshheading:16119242... | lld:pubmed |
| pubmed-article:16119242 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16119242 | pubmed:articleTitle | Selective recording of the canine hypoglossal nerve using a multicontact flat interface nerve electrode. | lld:pubmed |
| pubmed-article:16119242 | pubmed:affiliation | Neural Engineering Center of the Biomedical Engineering Department, Case Western Reserve University, Cleveland, OH 44106, USA. pby2@duke.edu | lld:pubmed |
| pubmed-article:16119242 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16119242 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:16119242 | pubmed:publicationType | Evaluation Studies | lld:pubmed |
| pubmed-article:16119242 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16119242 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16119242 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16119242 | lld:pubmed |
