|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007137,
umls-concept:C0034802,
umls-concept:C0205554,
umls-concept:C0392762,
umls-concept:C0521367,
umls-concept:C0521447,
umls-concept:C0521449,
umls-concept:C0597360,
umls-concept:C0680730,
umls-concept:C0751688,
umls-concept:C0936012,
umls-concept:C1148554
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|
pubmed:issue |
16
|
|
pubmed:dateCreated |
2005-8-23
|
|
pubmed:abstractText |
Several lines of evidence support the epidermal growth factor receptor (EGFR) as a molecular target for therapy in head and neck squamous cell carcinomas (HNSCC). Determination of tumor EGFR levels by conventional immunohistochemistry has not always predicted antitumor efficacy. Quantitative assays may provide more accurate assessment of the level of EGFR receptor in the tumor, which may thus provide more reliable prognostic and predictive information. We studied the prognostic value of quantitative assessment of EGFR in oropharyngeal squamous cell cancers treated with radiotherapy.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
1078-0432
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
15
|
|
pubmed:volume |
11
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
5856-62
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|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:16115926-Adult,
pubmed-meshheading:16115926-Aged,
pubmed-meshheading:16115926-Cell Nucleus,
pubmed-meshheading:16115926-Cohort Studies,
pubmed-meshheading:16115926-Cytoplasm,
pubmed-meshheading:16115926-Female,
pubmed-meshheading:16115926-Humans,
pubmed-meshheading:16115926-Image Processing, Computer-Assisted,
pubmed-meshheading:16115926-Immunohistochemistry,
pubmed-meshheading:16115926-Male,
pubmed-meshheading:16115926-Middle Aged,
pubmed-meshheading:16115926-Multivariate Analysis,
pubmed-meshheading:16115926-Neoplasm Staging,
pubmed-meshheading:16115926-Neoplasms, Squamous Cell,
pubmed-meshheading:16115926-Oropharyngeal Neoplasms,
pubmed-meshheading:16115926-Receptor, Epidermal Growth Factor,
pubmed-meshheading:16115926-Reproducibility of Results,
pubmed-meshheading:16115926-Survival Analysis
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|
pubmed:year |
2005
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|
pubmed:articleTitle |
Quantitative determination of nuclear and cytoplasmic epidermal growth factor receptor expression in oropharyngeal squamous cell cancer by using automated quantitative analysis.
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|
pubmed:affiliation |
Department of Medical Oncology, Yale University School of Medicine, New Haven, Connecticut, USA.
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|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
