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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2006-1-23
pubmed:abstractText
A growing body of evidence indicates that pregnancy-induced hypertension can be associated with features of insulin resistance. However, the impact of lower than hypertension-levels of blood pressure in pregnancy on the subsequent risk of developing abnormal glucose tolerance (AGT), has not been examined. We investigated women born in the years 1933-1956 and living in the municipality of Savitaipale, Finland, in May 1996. Prevalence of AGT was assessed by using oral glucose tolerance tests (OGTT). A retrospective chart review was carried out with regard to 216 nulliparas to obtain late pregnancy blood pressures. Logistic regression analyses showed that, after adjusting for body mass index (BMI) and age at OGTT, as well as for the number of subsequent pregnancies and the use of antihypertensive medication for PIH, 1 mmHg increase in systolic and diastolic blood pressure at late pregnancy in nulliparas increased the probability for AGT later in life 1.04-fold (OR, 1.04; 95% confidence interval, 1.00-1.09) and 1.06-fold (OR, 1.06; 95% confidence interval, 1.02-1.11), respectively. The results of this study suggest that not only hypertension but also less elevated levels of blood pressure during late pregnancy in nulliparas may be used as a predictor of subsequent AGT.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0168-8227
pubmed:author
pubmed:issnType
Print
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
220-4
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Late pregnancy blood pressure in nulliparas and subsequent abnormal glucose tolerance.
pubmed:affiliation
Savitaipale Health Centre, Maitolantie 7, FIN-54800 Savitaipale, Finland.
pubmed:publicationType
Journal Article