Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2005-8-15
pubmed:abstractText
Cerebral infarction is an uncommon complication in multiple myeloma with hyperviscosity. Serum hyperviscosity may cause a variety of clinical manifestations including bleeding from mucosal membranes, congestive heart failure, retinopathy, and various neurologic deficits. These manifestations have been attributed to the presence of large quantities of asymmetrical molecules of high molecular weight in the serum. We recently experienced a case of multiple myeloma with acute cerebral infarction, which caused by hyperviscosity, as an initial manifestation in IgG multiple myeloma, and reviewed the relevant literature of myeloma presenting with the stroke. A 68-yr-old woman abruptly developed hypesthesia and monoplegia in the left leg. The stroke confirmed by the brain MRI and MR angiography, which revealed acute infarction at the right anterior cerebral artery territory. On admission, routine blood tests showed a slight decrease in hemoglobin and a marked increase in erythrocyte sedimentation rate. Peripheral blood smear, serum protein electrophoresis, serum visocity, and bone marrow aspiration showed that she had IgG multiple myeloma with hyperviscosity. She was treated by chemotherapy with cyclophosphamide and discharged with the improved clinical condition.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/16100471-10867211, http://linkedlifedata.com/resource/pubmed/commentcorrection/16100471-11411261, http://linkedlifedata.com/resource/pubmed/commentcorrection/16100471-11583027, http://linkedlifedata.com/resource/pubmed/commentcorrection/16100471-14284847, http://linkedlifedata.com/resource/pubmed/commentcorrection/16100471-14631546, http://linkedlifedata.com/resource/pubmed/commentcorrection/16100471-2003279, http://linkedlifedata.com/resource/pubmed/commentcorrection/16100471-4644164, http://linkedlifedata.com/resource/pubmed/commentcorrection/16100471-4701949, http://linkedlifedata.com/resource/pubmed/commentcorrection/16100471-646950, http://linkedlifedata.com/resource/pubmed/commentcorrection/16100471-6681548, http://linkedlifedata.com/resource/pubmed/commentcorrection/16100471-9513339
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1011-8934
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
699-701
pubmed:dateRevised
2010-9-20
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Cerebral infarction in IgG multiple myeloma with hyperviscosity.
pubmed:affiliation
Deptment of Neurology, Chonnam National University Medical School, Korea.
pubmed:publicationType
Journal Article, Case Reports