Source:http://linkedlifedata.com/resource/pubmed/id/16094567
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2005-8-11
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pubmed:abstractText |
The clinical efficacy of tulathromycin in the treatment of natural outbreaks of swine respiratory disease (SRD) was evaluated at five European sites. Pigs (1 to 6 months of age) exhibiting clinical signs of SRD were treated intramuscularly with tulathromycin (n = 247) at 2.5 mg/kg on day 0 versus either tiamulin (n = 102) at 15 mg/kg on days 0, 1, and 2 (Germany, the Netherlands, and the United Kingdom) or florfenicol (n = 20) at 15 mg/kg on days 0 and 2 (France). Actinobacillus pleuropneumoniae, Pasteurella multocida, and Mycoplasma hyopneumoniae infections were the most frequently diagnosed pathogens. For both tulathromycin-treated animals and those treated with tiamulin or florfenicol, there were significant (P = .0001) reductions in mean rectal temperature and the severity of abnormal clinical signs on days 2 and 10 compared with day 0. There were no significant differences (P > .05) between treatments in average daily weight gain. Tulathromycin was found to be safe and highly effective in the treatment of natural outbreaks of SRD.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Disaccharides,
http://linkedlifedata.com/resource/pubmed/chemical/Diterpenes,
http://linkedlifedata.com/resource/pubmed/chemical/Heterocyclic Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Thiamphenicol,
http://linkedlifedata.com/resource/pubmed/chemical/florfenicol,
http://linkedlifedata.com/resource/pubmed/chemical/tiamulin,
http://linkedlifedata.com/resource/pubmed/chemical/tulathromycin
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pubmed:status |
MEDLINE
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pubmed:issn |
1528-3593
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
203-13
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16094567-Animals,
pubmed-meshheading:16094567-Anti-Bacterial Agents,
pubmed-meshheading:16094567-Disaccharides,
pubmed-meshheading:16094567-Disease Outbreaks,
pubmed-meshheading:16094567-Diterpenes,
pubmed-meshheading:16094567-Europe,
pubmed-meshheading:16094567-Heterocyclic Compounds,
pubmed-meshheading:16094567-Injections, Intramuscular,
pubmed-meshheading:16094567-Pasteurellosis, Pneumonic,
pubmed-meshheading:16094567-Severity of Illness Index,
pubmed-meshheading:16094567-Swine,
pubmed-meshheading:16094567-Swine Diseases,
pubmed-meshheading:16094567-Thiamphenicol,
pubmed-meshheading:16094567-Treatment Outcome
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pubmed:year |
2005
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pubmed:articleTitle |
Evaluation of the therapeutic activity of tulathromycin against swine respiratory disease on farms in Europe.
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pubmed:affiliation |
Veterinary Medicine Research and Development, Pfizer Ltd, Sandwich, Kent, UK.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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