16093917

Source:http://linkedlifedata.com/resource/pubmed/id/16093917

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0001811, umls-concept:C0020538, umls-concept:C0059285, umls-concept:C0205191, umls-concept:C0332206, umls-concept:C0623362, umls-concept:C0678226, umls-concept:C1280500, umls-concept:C1515926, umls-concept:C1801960
pubmed:issue	9
pubmed:dateCreated	2005-8-11
pubmed:abstractText	To determine the effects of age and dual endothelin (ET)A/ETB receptor antagonism (bosentan) on aortic matrix metalloproteinase (MMP) abundance and tissue inhibitor of metalloproteinase (TIMP) expression in normotensive Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR).
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8306882
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antihypertensive Agents, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Precursors, http://linkedlifedata.com/resource/pubmed/chemical/Gelatinases, http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 2, http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinases, http://linkedlifedata.com/resource/pubmed/chemical/Metalloendopeptidases, http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Endothelin A, http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Endothelin B, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Endothelin, http://linkedlifedata.com/resource/pubmed/chemical/Sulfonamides, http://linkedlifedata.com/resource/pubmed/chemical/bosentan, http://linkedlifedata.com/resource/pubmed/chemical/progelatinase
pubmed:status	MEDLINE
pubmed:month	Sep
pubmed:issn	0263-6352
pubmed:author	pubmed-author:EdgeGillianG, pubmed-author:HennessyMartinaM, pubmed-author:KelsoElizabeth JEJ, pubmed-author:McDermottBarbara JBJ, pubmed-author:SiahWei FWF, pubmed-author:SongGuojieG, pubmed-author:SpiersJames PJP
pubmed:issnType	Print
pubmed:volume	23
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1717-24
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:16093917-Aging, pubmed-meshheading:16093917-Animals, pubmed-meshheading:16093917-Antihypertensive Agents, pubmed-meshheading:16093917-Aorta, Thoracic, pubmed-meshheading:16093917-Blotting, Western, pubmed-meshheading:16093917-Endothelium, Vascular, pubmed-meshheading:16093917-Enzyme Precursors, pubmed-meshheading:16093917-Gelatinases, pubmed-meshheading:16093917-Hypertension, pubmed-meshheading:16093917-Male, pubmed-meshheading:16093917-Matrix Metalloproteinase 2, pubmed-meshheading:16093917-Matrix Metalloproteinases, pubmed-meshheading:16093917-Metalloendopeptidases, pubmed-meshheading:16093917-Microscopy, Fluorescence, pubmed-meshheading:16093917-Rats, pubmed-meshheading:16093917-Rats, Inbred SHR, pubmed-meshheading:16093917-Rats, Inbred WKY, pubmed-meshheading:16093917-Receptor, Endothelin A, pubmed-meshheading:16093917-Receptor, Endothelin B, pubmed-meshheading:16093917-Receptors, Endothelin, pubmed-meshheading:16093917-Reference Standards, pubmed-meshheading:16093917-Sulfonamides
pubmed:year	2005
pubmed:articleTitle	Alterations in vascular matrix metalloproteinase due to ageing and chronic hypertension: effects of endothelin receptor blockade.
pubmed:affiliation	Department of Pharmacology and Therapeutics, Trinity Centre for Health Sciences, Trinity College Dublin, St. James's Hospital, James's Street, Dublin 8, Ireland. spiersj@tcd.ie
pubmed:publicationType	Journal Article, Comparative Study, Research Support, Non-U.S. Gov't