Source:http://linkedlifedata.com/resource/pubmed/id/16088806
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2005-8-9
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pubmed:abstractText |
To determine the distribution of rotavirus strain genotypes in South Korea, rotavirus-positive stool specimens were collected from July 2002 through June 2003 at 8 hospitals in the Korean Rotavirus Strain Surveillance Network, and they were genotyped by means of reverse-transcription polymerase chain reaction. The globally uncommon G4P[6] type was the most prevalent type identified among strains (27% of strains), the newly emerging G9P[8] strain accounted for 11% of strains, and the globally common genotypes (i.e., G1P[8], G2P[4], G3P[8], and G4P[8]) constituted 55% of the strains characterized. Ninety percent of G4P[6] strains were detected in specimens obtained from neonates. Common genotypes were responsible for the rotavirus epidemic that began in January 2003 and ended in May 2003; however, an early peak in infections with the G4P[6] strain occurred from August through October 2002, and infections with this strain were detected throughout the remaining study period. G4P[6] strains were most commonly identified at 6 urban health care centers, but they were absent from 2 rural health care centers. The newly emerging strain G9P[8] represented a relatively greater proportion of strains identified at a hospital in the central region of Korea and at 2 hospitals in the southern region. The identification of novel rotavirus genotypes in this laboratory-based surveillance study underscores the importance to public health of continued strain surveillance among children for whom prevention of rotavirus infection by vaccination might be considered.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-1899
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pubmed:author |
pubmed-author:BreseeJosephJ,
pubmed-author:ChangChulhunC,
pubmed-author:ChoiSukwooS,
pubmed-author:GentschJonJ,
pubmed-author:GlassRogerR,
pubmed-author:JangSookjinS,
pubmed-author:KangJung OakJO,
pubmed-author:KilgorePaulP,
pubmed-author:KimJeongukJ,
pubmed-author:KimJung SooJS,
pubmed-author:KimMi-NaMN,
pubmed-author:NyambatBatmunkhB,
pubmed-author:SuhHun SukHS,
pubmed-author:YoonYeominY
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
192 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S57-63
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16088806-Child, Preschool,
pubmed-meshheading:16088806-Genotype,
pubmed-meshheading:16088806-Hospitals,
pubmed-meshheading:16088806-Humans,
pubmed-meshheading:16088806-Infant,
pubmed-meshheading:16088806-Infant, Newborn,
pubmed-meshheading:16088806-Korea,
pubmed-meshheading:16088806-Molecular Epidemiology,
pubmed-meshheading:16088806-Rotavirus,
pubmed-meshheading:16088806-Rotavirus Infections,
pubmed-meshheading:16088806-Seasons,
pubmed-meshheading:16088806-Sentinel Surveillance
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pubmed:year |
2005
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pubmed:articleTitle |
Molecular epidemiological profile of rotavirus in South Korea, July 2002 through June 2003: emergence of G4P[6] and G9P[8] strains.
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pubmed:affiliation |
Department of Laboratory Medicine, Hanyang University Guri Hospital, Guri, Gyunggido, South Korea. jokang@hanyang.ac.kr
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study
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