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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2005-10-10
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pubmed:abstractText |
Beside its well-known function as tumour suppressor gene, p53 is supposed to positively regulate cell division and cell differentiation. Because hepatocyte proliferation has been reported to be reduced by blockade of p53 function in vitro, we examined in the present study the impact of p53 inhibition on hepatocyte proliferation in vivo.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0168-8278
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
829-35
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16087272-Animals,
pubmed-meshheading:16087272-Apoptosis,
pubmed-meshheading:16087272-Benzothiazoles,
pubmed-meshheading:16087272-Cyclin-Dependent Kinase Inhibitor p21,
pubmed-meshheading:16087272-Hepatectomy,
pubmed-meshheading:16087272-Hepatocytes,
pubmed-meshheading:16087272-In Situ Nick-End Labeling,
pubmed-meshheading:16087272-Liver Regeneration,
pubmed-meshheading:16087272-Male,
pubmed-meshheading:16087272-Mice,
pubmed-meshheading:16087272-Mice, Inbred C57BL,
pubmed-meshheading:16087272-Organ Size,
pubmed-meshheading:16087272-Proliferating Cell Nuclear Antigen,
pubmed-meshheading:16087272-Thiazoles,
pubmed-meshheading:16087272-Toluene,
pubmed-meshheading:16087272-Tumor Suppressor Protein p53
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pubmed:year |
2005
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pubmed:articleTitle |
Pifithrin-alpha induced p53 inhibition does not affect liver regeneration after partial hepatectomy in mice.
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pubmed:affiliation |
Department of Experimental Surgery, University of Rostock, Schillingallee 70, 18055 Rostock, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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