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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2005-8-8
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pubmed:abstractText |
Serine protease inhibitor Kazal type 1 (SPINK1), which is structurally similar to epidermal growth factor, is thought to inhibit trypsin activity and to prevent pancreatitis. Point mutations in the SPINK1 gene seem to predispose humans to pancreatitis; however, the clinical significance of SPINK1 mutations remains controversial. This study aimed to elucidate the role of SPINK1.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:ArakiKimiK,
pubmed-author:ArakiMasatakeM,
pubmed-author:HarunaKyokoK,
pubmed-author:HirotaMasahikoM,
pubmed-author:KumeShoenS,
pubmed-author:MatsuiMakotoM,
pubmed-author:MizumotoTakaoT,
pubmed-author:MizushimaNoboruN,
pubmed-author:OgawaMichioM,
pubmed-author:OhmurayaMasakiM,
pubmed-author:TakeyaMotohiroM,
pubmed-author:YamamuraKen-IchiK
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pubmed:issnType |
Print
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pubmed:volume |
129
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
696-705
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16083722-Animals,
pubmed-meshheading:16083722-Biopsy, Needle,
pubmed-meshheading:16083722-Blotting, Western,
pubmed-meshheading:16083722-Caerulein,
pubmed-meshheading:16083722-Cell Death,
pubmed-meshheading:16083722-Cells, Cultured,
pubmed-meshheading:16083722-DNA,
pubmed-meshheading:16083722-Disease Models, Animal,
pubmed-meshheading:16083722-Immunohistochemistry,
pubmed-meshheading:16083722-Mice,
pubmed-meshheading:16083722-Mice, Inbred C57BL,
pubmed-meshheading:16083722-Mice, Transgenic,
pubmed-meshheading:16083722-Pancreas,
pubmed-meshheading:16083722-Pancreatic Function Tests,
pubmed-meshheading:16083722-Pancreatitis,
pubmed-meshheading:16083722-Phagocytosis,
pubmed-meshheading:16083722-RNA,
pubmed-meshheading:16083722-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16083722-Sensitivity and Specificity,
pubmed-meshheading:16083722-Serine Proteinase Inhibitors,
pubmed-meshheading:16083722-Trypsin Inhibitor, Kazal Pancreatic
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pubmed:year |
2005
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pubmed:articleTitle |
Autophagic cell death of pancreatic acinar cells in serine protease inhibitor Kazal type 3-deficient mice.
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pubmed:affiliation |
Division of Developmental Genetics, Institute of Molecular Embryology and Genetics, Kumamoto University, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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