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pubmed-article:16083499pubmed:abstractTextCyclooxygenase 2 (COX-2), the inducible form of prostaglandin G/H synthase, is associated with several human cancers including pancreatic adenocarcinoma. Pancreatic stellate cells (PSCs) play a central role in the intense desmoplasia that surrounds pancreatic adenocarcinoma. The present study examined COX-2 expression in PSCs. PSCs isolated from normal rats, were cultured and exposed to conditioned medium (CM) from the human pancreatic cell line, PANC-1.lld:pubmed
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pubmed-article:16083499pubmed:articleTitlePancreatic stellate cells (PSCs) express cyclooxygenase-2 (COX-2) and pancreatic cancer stimulates COX-2 in PSCs.lld:pubmed
pubmed-article:16083499pubmed:affiliationDepartment of Surgery, Robert H Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, 333 East Superior 4-713, Chicago, IL 60611, USA. yansei@jf7.so-net.ne.jplld:pubmed
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