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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
8
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pubmed:dateCreated |
2005-8-5
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pubmed:abstractText |
The pathogenesis of chronic hepatitis C virus (HCV) infection is associated with a defective host antiviral immune response and intrahepatic oxidative stress. Oxidative stress and lipid peroxidation play major roles in the fatty liver accumulation (steatosis) that leads to necro-inflammation and necrosis of hepatic cells. Previous trials suggested that antioxidative therapy may have a beneficial effect on patients with chronic HCV infection.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0192-0790
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pubmed:author |
pubmed-author:AckermanZviZ,
pubmed-author:CohenRobertR,
pubmed-author:HemedNillaN,
pubmed-author:IlanYaronY,
pubmed-author:IsraeliEranE,
pubmed-author:MelhemAllaA,
pubmed-author:OhanaHanaH,
pubmed-author:PappoOritO,
pubmed-author:RoweMinaM,
pubmed-author:ShiboletOrenO,
pubmed-author:SternMirelaM,
pubmed-author:ZabreckyGeorgeG
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pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
737-42
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16082287-Adolescent,
pubmed-meshheading:16082287-Adult,
pubmed-meshheading:16082287-Aged,
pubmed-meshheading:16082287-Antioxidants,
pubmed-meshheading:16082287-Biopsy,
pubmed-meshheading:16082287-Drug Therapy, Combination,
pubmed-meshheading:16082287-Female,
pubmed-meshheading:16082287-Follow-Up Studies,
pubmed-meshheading:16082287-Hepacivirus,
pubmed-meshheading:16082287-Hepatitis C, Chronic,
pubmed-meshheading:16082287-Humans,
pubmed-meshheading:16082287-Liver,
pubmed-meshheading:16082287-Male,
pubmed-meshheading:16082287-Middle Aged,
pubmed-meshheading:16082287-Questionnaires,
pubmed-meshheading:16082287-RNA, Viral,
pubmed-meshheading:16082287-Treatment Outcome
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pubmed:year |
2005
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pubmed:articleTitle |
Treatment of chronic hepatitis C virus infection via antioxidants: results of a phase I clinical trial.
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pubmed:affiliation |
Liver Unit, Department of Medicine, Hebrew University, Hadassah Medical Center, Jerusalem, Israel.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase I
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