Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2005-8-5
pubmed:abstractText
Streptococcus agalactiae, also designated group B streptococcus (GBS), is an important pathogen in neonates, pregnant women, and nonpregnant adults with predisposing conditions. We used multilocus sequence typing (MLST) to characterize 158 GBS isolates that were associated with neonatal and adult invasive disease and that were collected in northern and western Sweden from 1988 to 1997. Five major genetic lineages (sequence type [ST] 19, ST-17, ST-1, ST-23, and ST-9 complexes) were identified among the isolates, including serotype Ia, Ib, and II to V isolates, indicating a highly clonal population structure among invasive GBS isolates. A number of STs were found to contain isolates of different serotypes, which indicates that capsule switching occurred rather frequently. Two distantly related genetic lineages were identified among isolates of serotype III, namely, clonal complex 19 (CC19), and CC17. CC19 was equally common among isolates from adult and neonatal disease (accounting for 10.3% of GBS isolates from adult disease and 18.7% from neonatal disease), whereas CC17 significantly appeared to be associated with neonatal invasive disease (isolated from 21.9% of neonatal isolates but only 2.6% of adult isolates). The distribution of the mobile elements GBSi1 and IS1548 reveals that they can act as genetic markers for lineages CC17 and CC19, respectively.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-10068604, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-10325343, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-10428995, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-10913080, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-10970395, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-11168030, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-11254602, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-11274116, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-11532154, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-11895961, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-12037054, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-12232847, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-12354221, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-12791877, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-12909368, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-14638773, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-14973027, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-14999614, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-15496242, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-2660146, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-324367, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-8567885, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-8568297, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-8641801, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-8990198, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-9466257, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-9533725, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-9534970, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-9534974, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-9534996, http://linkedlifedata.com/resource/pubmed/commentcorrection/16081902-9563251
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0095-1137
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3727-33
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Multilocus sequence typing of Swedish invasive group B streptococcus isolates indicates a neonatally associated genetic lineage and capsule switching.
pubmed:affiliation
Department of Biomedical Laboratory Science, Umeå University, S-90 185 Umeå, Sweden. shilu.luan@climi.umu.se
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't