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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2005-8-5
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pubmed:abstractText |
Inhaled nitric oxide (iNO) is proposed in the management of pulmonary hypertension (PH) in patients undergoing cardiac surgery. Secondary PH related to a long-standing heart valve disease however may be refractory to iNO. Aim of this prospective study was to determine whether the combination of iNO plus dipyridamole (DP), a cyclic guanosine monophosphate-specific phosphodiesterase inhibitor (PDE5), may enhance and/or prolong the response to iNO in adult patients with secondary valve-related PH undergoing cardiac surgery, and attenuate rebound events related to its discontinuation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0167-5273
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
18
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
156-63
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16080974-Administration, Inhalation,
pubmed-meshheading:16080974-Aged,
pubmed-meshheading:16080974-Analysis of Variance,
pubmed-meshheading:16080974-Aortic Valve,
pubmed-meshheading:16080974-Bronchodilator Agents,
pubmed-meshheading:16080974-Cardiac Output,
pubmed-meshheading:16080974-Dipyridamole,
pubmed-meshheading:16080974-Drug Therapy, Combination,
pubmed-meshheading:16080974-Female,
pubmed-meshheading:16080974-Heart Valve Diseases,
pubmed-meshheading:16080974-Heart Valve Prosthesis Implantation,
pubmed-meshheading:16080974-Humans,
pubmed-meshheading:16080974-Hypertension, Pulmonary,
pubmed-meshheading:16080974-Male,
pubmed-meshheading:16080974-Middle Aged,
pubmed-meshheading:16080974-Mitral Valve,
pubmed-meshheading:16080974-Nitric Oxide,
pubmed-meshheading:16080974-Oxygen Consumption,
pubmed-meshheading:16080974-Phosphodiesterase Inhibitors,
pubmed-meshheading:16080974-Prospective Studies,
pubmed-meshheading:16080974-Pulmonary Circulation,
pubmed-meshheading:16080974-Pulmonary Wedge Pressure,
pubmed-meshheading:16080974-Treatment Outcome,
pubmed-meshheading:16080974-Vascular Resistance
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pubmed:year |
2005
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pubmed:articleTitle |
Hemodynamic effects of inhaled nitric oxide and phosphodiesterase inhibitor (dipyridamole) on secondary pulmonary hypertension following heart valve surgery in adults.
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pubmed:affiliation |
Division of Cardiac Surgery and Anesthesiology, University of Verona, OCM Borgo Trento, Piazzale Stefani 1, 37126, Verona, Italy. fsant@yahoo.com
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pubmed:publicationType |
Journal Article,
Comparative Study
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