Linked Life Data

16080506

Source:http://linkedlifedata.com/resource/pubmed/id/16080506

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2005-8-5
pubmed:abstractText
RNA helicases constitute a large group of enzymes involved in all aspects of RNA metabolism. Several RNA helicases are dysregulated in cancer, whereas several others are involved in differentiation. DHX32 has previously been identified as a novel RNA helicase with a unique structure and expression pattern. DHX32 message was down-regulated in acute lymphoblastic leukemia cell lines and patient samples. In this report, anti-DHX32 was used to study its expression in thymus. Immunohistochemistry and flow cytometry showed positive correlation of DHX32 expression with thymocyte maturation. These results suggest that DHX32 might play a role in normal lymphocyte differentiation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0250-7005
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2645-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:articleTitle
DHX32 expression suggests a role in lymphocyte differentiation.
pubmed:affiliation
Department of Paediatric, Laboratory Medicine, Hospital for Sick Children, University of Toronto, Canada. Mohamed.abdelhaleem@sickkids.ca
pubmed:publicationType
Journal Article