Source:http://linkedlifedata.com/resource/pubmed/id/16078937
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
2005-8-4
|
pubmed:abstractText |
Pain and discomfort are the leading cause for consultative visits to gastroenterologists. Acute pain should be considered a symptom of an underlying disease, thereby serving a physiologically important function. However, many patients experience chronic pain in the absence of potentially harmful stimuli or disorders, turning pain into the primary problem rather than a symptom. Vagal and spinal afferents both contribute to the sensory component of the gut-brain axis. Current evidence suggests that they convey different elements of the complex sensory experience. Spinal afferents play a key role in the discriminatory dimension, while vagal input primarily affects the strong emotional and autonomic reactions to noxious visceral stimuli. Drugs, surgical and non-pharmacological treatments can target these pathways and provide therapeutic options for patients with chronic visceral pain syndromes.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
1350-1925
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
17
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
488-99
|
pubmed:dateRevised |
2006-11-7
|
pubmed:meshHeading | |
pubmed:year |
2005
|
pubmed:articleTitle |
Basic and clinical aspects of visceral sensation: transmission in the CNS.
|
pubmed:affiliation |
Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA. bielefeldtk@dom.pitt.edu
|
pubmed:publicationType |
Journal Article,
Review
|