Linked Life Data

16073434

Source:http://linkedlifedata.com/resource/pubmed/id/16073434

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5607
pubmed:dateCreated
2005-8-2
pubmed:abstractText
When frog skeletal muscle fibres are bathed in solutions containing Cs(+) and K(+) in the ratio 1:4,000, a reduction is observed in the size of inward K currents through the resting membrane. This effect is enhanced by an increase in either hyperpolarisation or external Cs(+) concentration. It can be predicted from these findings that regenerative changes in membrane potential should be obtainable in fibres, in the presence of Cs(+), that are hyperpolarised by means of a current electrode. Such responses are described in the last part of this report. In squid axon and frog node, internal Cs(+) produces a voltage-dependent block of the delayed, outward K currents, though the ratio of Cs(+) to K(+) required for this effect is far greater than that used in the experiments reported here. A closer parallel can be drawn between our findings and those recently reported on the inward K currents in the starfish egg cell.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0028-0836
pubmed:author
pubmed:issnType
Print
pubmed:day
12
pubmed:volume
267
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
169-70
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Cs(+) causes a voltage-dependent block of inward K currents in resting skeletal muscle fibres.
pubmed:affiliation
Department of Physiology, University of Leicester, UK.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't