Linked Life Data

16060536

Source:http://linkedlifedata.com/resource/pubmed/id/16060536

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2005-8-2
pubmed:abstractText
The temporomandibular joint (TMJ) disc is a central element in several TMJ disorders. Tissue-engineered TMJ disc replacements may alleviate discomfort associated with TMJ disorders; however, prior to developing a replacement, a thorough understanding of the native disc must be attained. Toward this end, we developed an unconfined compression, incremental stress relaxation viscoelastic model which simultaneously incorporates the strain increment magnitude and total deformation in the stress relaxation solution. This multiple strain step model was fit to stress relaxation data from (i) 80 test sites from eight porcine TMJ discs for the purposes of a surface-regional characterization and (ii) 30 test sites from five porcine TMJ discs for the purposes of a freeze-thaw characterization. The model estimated viscoelastic parameters accurately and surface-regional variations were detected throughout the TMJ disc. Regionally, the medial and anterior regions have the largest relaxation moduli, and the posterior and anterior regions have the largest instantaneous moduli. The inferior surface was found to have higher instantaneous modulus values than the superior surface. Furthermore, material properties were retained over five freeze-thaw cycles. The results of this study allow for the creation of design and validation criteria for future engineering efforts and shed light on the disc's role in TMJ function and dysfunction.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0090-6964
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
951-62
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
A surface-regional and freeze-thaw characterization of the porcine temporomandibular joint disc.
pubmed:affiliation
Department of Bioengineering, Rice University, Houston, TX 77251-1892, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, N.I.H., Extramural