Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2005-8-2
pubmed:abstractText
The objective of this research was to study the effectiveness of NaFeEDTA-fortified soy sauce for controlling iron deficiency in a high-risk population. This was an 18-month, randomized, placebo-controlled intervention trial in 14,000 residents aged three years or older in Bijie City, Guizhou Province, China, using sodium-iron ethylene diamine tetraacetate (NaFeEDTA)-fortified soy sauce (29.6 mg Fe/100 ml). The study data included measurements of food consumption, hemoglobin, serum ferritin, and serum retinol. The results showed that the diet consisted primarily of cereals, fruits, and vegetables, with very little meat. Food consumption remained unchanged during the study period and was similar in the fortified and control groups. The average daily soy sauce consumption of the group consuming the fortified product was 16.4 ml per person, which provided 4.9 mg of iron from NaFeEDTA. At the end of the trial, all age and sex subgroups receiving NaFeEDTA had significantly higher hemoglobin levels, a lower prevalence of anemia, and higher plasma ferritin levels than the controls. The effects became statistically significant after six months of intervention and were maintained throughout the study period. We conclude that NaFeEDTA-fortified soy sauce was highly effective in controlling iron deficiency and reducing the prevalence of iron-deficiency anemia in men, women, and children. NaFeEDTA-fortified soy sauce is affordable and was well accepted by the study population.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0379-5721
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
177-86; discussion 187-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:16060219-Adolescent, pubmed-meshheading:16060219-Adult, pubmed-meshheading:16060219-Anemia, Iron-Deficiency, pubmed-meshheading:16060219-Child, pubmed-meshheading:16060219-Child, Preschool, pubmed-meshheading:16060219-China, pubmed-meshheading:16060219-Diet Surveys, pubmed-meshheading:16060219-Double-Blind Method, pubmed-meshheading:16060219-Edetic Acid, pubmed-meshheading:16060219-Female, pubmed-meshheading:16060219-Ferric Compounds, pubmed-meshheading:16060219-Ferritins, pubmed-meshheading:16060219-Food, Fortified, pubmed-meshheading:16060219-Hemoglobins, pubmed-meshheading:16060219-Humans, pubmed-meshheading:16060219-Iron, pubmed-meshheading:16060219-Iron, Dietary, pubmed-meshheading:16060219-Male, pubmed-meshheading:16060219-Middle Aged, pubmed-meshheading:16060219-Questionnaires, pubmed-meshheading:16060219-Soy Foods
pubmed:year
2005
pubmed:articleTitle
Studies on the effectiveness of NaFeEDTA-fortified soy sauce in controlling iron deficiency: a population-based intervention trial.
pubmed:affiliation
Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing, China jshchen@ilsichina.org
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial, Research Support, Non-U.S. Gov't