pubmed:abstractText |
A transcription factor cascade drives adipogenesis. Two new members of this cascade have been uncovered--Kruppel-like factor 5 (KLF5), which is induced by C/EBPbeta and delta and acts in concert with C/EBPalpha, beta, and delta to activate PPARgamma2 expression, and Krox20, which is upstream of C/EBPbeta expression and one of the earliest factors induced during adipogenesis.
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pubmed:affiliation |
Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Building 37, Room 3106, Bethesda, Maryland 20892, USA.
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