| pubmed-article:16052542 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16052542 | lifeskim:mentions | umls-concept:C0205199 | lld:lifeskim |
| pubmed-article:16052542 | lifeskim:mentions | umls-concept:C0030685 | lld:lifeskim |
| pubmed-article:16052542 | lifeskim:mentions | umls-concept:C0680255 | lld:lifeskim |
| pubmed-article:16052542 | lifeskim:mentions | umls-concept:C0391871 | lld:lifeskim |
| pubmed-article:16052542 | lifeskim:mentions | umls-concept:C1283071 | lld:lifeskim |
| pubmed-article:16052542 | lifeskim:mentions | umls-concept:C1963578 | lld:lifeskim |
| pubmed-article:16052542 | lifeskim:mentions | umls-concept:C0164202 | lld:lifeskim |
| pubmed-article:16052542 | lifeskim:mentions | umls-concept:C0377492 | lld:lifeskim |
| pubmed-article:16052542 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:16052542 | pubmed:dateCreated | 2005-8-3 | lld:pubmed |
| pubmed-article:16052542 | pubmed:abstractText | Addition of biodegradable polymer shells surrounding polymeric, drug-loaded microparticles offers the opportunity to control drug release rates. A novel fabrication method was used to produce microparticles with precise control of particle diameter and the thickness of the polymer shell. The effect of shell thickness on release of a model drug, piroxicam, has been clearly shown for 2- to 15-microm thick shells of poly(D,L-lactide) (PDLL) surrounding a poly(D,L-lactide-co-glycolide) (PLG) core and compared to pure PLG microspheres loaded with piroxicam. Furthermore, the core-shell microparticles are compared to microspheres containing blended polymers in the same mass ratios to demonstrate the importance of the core-shell morphology. Combining PDLL(PLG) microcapsules of different shell thicknesses allows nearly constant release rates to be attained for a period of 6 weeks. | lld:pubmed |
| pubmed-article:16052542 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16052542 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16052542 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16052542 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16052542 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16052542 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16052542 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16052542 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16052542 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16052542 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16052542 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16052542 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16052542 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16052542 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16052542 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:16052542 | pubmed:issn | 0022-3549 | lld:pubmed |
| pubmed-article:16052542 | pubmed:author | pubmed-author:PackDaniel... | lld:pubmed |
| pubmed-article:16052542 | pubmed:author | pubmed-author:KimKyekyoon... | lld:pubmed |
| pubmed-article:16052542 | pubmed:author | pubmed-author:PollaufEmily... | lld:pubmed |
| pubmed-article:16052542 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16052542 | pubmed:volume | 94 | lld:pubmed |
| pubmed-article:16052542 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16052542 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16052542 | pubmed:pagination | 2013-22 | lld:pubmed |
| pubmed-article:16052542 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:16052542 | pubmed:meshHeading | pubmed-meshheading:16052542... | lld:pubmed |
| pubmed-article:16052542 | pubmed:meshHeading | pubmed-meshheading:16052542... | lld:pubmed |
| pubmed-article:16052542 | pubmed:meshHeading | pubmed-meshheading:16052542... | lld:pubmed |
| pubmed-article:16052542 | pubmed:meshHeading | pubmed-meshheading:16052542... | lld:pubmed |
| pubmed-article:16052542 | pubmed:meshHeading | pubmed-meshheading:16052542... | lld:pubmed |
| pubmed-article:16052542 | pubmed:meshHeading | pubmed-meshheading:16052542... | lld:pubmed |
| pubmed-article:16052542 | pubmed:meshHeading | pubmed-meshheading:16052542... | lld:pubmed |
| pubmed-article:16052542 | pubmed:meshHeading | pubmed-meshheading:16052542... | lld:pubmed |
| pubmed-article:16052542 | pubmed:meshHeading | pubmed-meshheading:16052542... | lld:pubmed |
| pubmed-article:16052542 | pubmed:meshHeading | pubmed-meshheading:16052542... | lld:pubmed |
| pubmed-article:16052542 | pubmed:meshHeading | pubmed-meshheading:16052542... | lld:pubmed |
| pubmed-article:16052542 | pubmed:meshHeading | pubmed-meshheading:16052542... | lld:pubmed |
| pubmed-article:16052542 | pubmed:meshHeading | pubmed-meshheading:16052542... | lld:pubmed |
| pubmed-article:16052542 | pubmed:meshHeading | pubmed-meshheading:16052542... | lld:pubmed |
| pubmed-article:16052542 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16052542 | pubmed:articleTitle | Small-molecule release from poly(D,L-lactide)/poly(D,L-lactide-co-glycolide) composite microparticles. | lld:pubmed |
| pubmed-article:16052542 | pubmed:affiliation | Department of Chemical and Biomolecular Engineering, University of Illinois, Urbana, Illinois, USA. | lld:pubmed |
| pubmed-article:16052542 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16052542 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:16052542 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:16052542 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
