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pubmed-article:16048400pubmed:abstractTextWe report a primary intraocular T-cell-rich large B-cell lymphoma in a 57-year-old woman who underwent 3 diagnostic vitrectomies for a presumed diagnosis of panuveitis. She developed no light perception in the left eye and underwent enucleation. Histopathologic and immunohistochemical studies on the enucleated globe disclosed a primary intraocular large B-cell lymphoma involving the choroid, vitreous, and retina. A large population of T cells was identified among the neoplastic B-cell population. B-cell immunoglobulin gene rearrangement and T-cell receptor gene rearrangement studies using the polymerase chain reaction method indicated that a monoclonal immunoglobulin kappa light chain population was present and that the T-cell population was not monoclonal. This case highlights the importance of interpreting cytologic features in vitreous aspirates in the context of the clinical situation.lld:pubmed
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pubmed-article:16048400pubmed:articleTitlePrimary intraocular T-cell-rich large B-cell lymphoma.lld:pubmed
pubmed-article:16048400pubmed:affiliationDepartment of Pathology, Duke University Medical Center, Durham, NC 27710, USA. cummi008@mc.duke.edulld:pubmed
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