Source:http://linkedlifedata.com/resource/pubmed/id/16048400
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2005-7-28
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pubmed:abstractText |
We report a primary intraocular T-cell-rich large B-cell lymphoma in a 57-year-old woman who underwent 3 diagnostic vitrectomies for a presumed diagnosis of panuveitis. She developed no light perception in the left eye and underwent enucleation. Histopathologic and immunohistochemical studies on the enucleated globe disclosed a primary intraocular large B-cell lymphoma involving the choroid, vitreous, and retina. A large population of T cells was identified among the neoplastic B-cell population. B-cell immunoglobulin gene rearrangement and T-cell receptor gene rearrangement studies using the polymerase chain reaction method indicated that a monoclonal immunoglobulin kappa light chain population was present and that the T-cell population was not monoclonal. This case highlights the importance of interpreting cytologic features in vitreous aspirates in the context of the clinical situation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1543-2165
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
129
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1050-3
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16048400-Clone Cells,
pubmed-meshheading:16048400-DNA, Neoplasm,
pubmed-meshheading:16048400-Eye Enucleation,
pubmed-meshheading:16048400-Eye Neoplasms,
pubmed-meshheading:16048400-Female,
pubmed-meshheading:16048400-Gene Rearrangement, B-Lymphocyte, Heavy Chain,
pubmed-meshheading:16048400-Gene Rearrangement, T-Lymphocyte,
pubmed-meshheading:16048400-Humans,
pubmed-meshheading:16048400-Lymphoma, B-Cell,
pubmed-meshheading:16048400-Lymphoma, Large B-Cell, Diffuse,
pubmed-meshheading:16048400-Middle Aged,
pubmed-meshheading:16048400-T-Lymphocytes,
pubmed-meshheading:16048400-Treatment Outcome,
pubmed-meshheading:16048400-Tumor Markers, Biological
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pubmed:year |
2005
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pubmed:articleTitle |
Primary intraocular T-cell-rich large B-cell lymphoma.
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pubmed:affiliation |
Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA. cummi008@mc.duke.edu
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pubmed:publicationType |
Journal Article,
Case Reports
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