Linked Life Data

16046721

Source:http://linkedlifedata.com/resource/pubmed/id/16046721

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2005-7-27
pubmed:abstractText
Pullulan and gamma-cyclodextrin are incompletely digestible, glucose-based, nonstructural carbohydrates synthesized by microorganisms. To determine their effect when incorporated into a complete liquid diet on ileal and total tract nutrient digestibility, ileal cannulated dogs (n = 8) were used in a repeated 4 x 4 Latin-square design. Twice daily, diets were offered containing 30% (DMB) maltodextrin, high-molecular-weight (MW) pullulan (MW 100,000), low-MW pullulan (MW 6300), or gamma-cyclodextrin. Fecal and ileal samples were collected for the last 4 d of each 10-d period. Dogs consuming high-MW pullulan had lower (P < 0.05) dry matter, organic matter, crude protein, fat, carbohydrate ileal and total tract digestibilities, and fecal DM, and higher (P < 0.05) fecal output and fecal scores (indicating looser stools). To evaluate glycemic and insulinemic responses to pullulans, food-deprived dogs consumed 25 g maltodextrin, high-MW pullulan, or low-MW pullulan in a repeated 3 x 3 Latin-square design. Glucose and insulin responses were determined for 180 min. Consumption of 25 g alpha-, beta-, and gamma-cyclodextrin resulted in regurgitation within 60 min. High-MW pullulan reduced (P < 0.05) blood glucose concentration at 15, 30, 45, and 60 min. Compared with maltodextrin, low-MW pullulan and gamma-cyclodextrin did not alter nutrient digestibilities or fecal characteristics to any extent, and low MW pullulan did not affect glycemic response. Although high MW pullulan decreased glycemic response, consumption of large amounts negatively affected nutrient digestibility and fecal characteristics.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0022-3166
pubmed:author
pubmed:issnType
Print
pubmed:volume
135
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1946-52
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Pullulans and gamma-cyclodextrin affect apparent digestibility and metabolism in healthy adult ileal cannulated dogs.
pubmed:affiliation
Department of Animal Sciences, University of Illinois, Urbana, 61801, USA.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't