Linked Life Data

16046115

Source:http://linkedlifedata.com/resource/pubmed/id/16046115

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
14
pubmed:dateCreated
2005-9-26
pubmed:abstractText
In this study, based on the Swedish Family-Cancer Database, risk factors and their population attributable fractions (PAFs) for endometrial cancer were studied. Over 700,000 women at ages 51-68 years, accumulating 23 million person-years at risk, were entered into Poisson analysis. Overall, reproductive factors (parity and age at last birth) showed a relative risk (RR) of 1.91 and a PAF of 45.51% when the reference group was women with a parity of 3+ and the last childbirth at ages over 34 years. The RR for family history was 2.33 but the PAF was only 2.09%. The RR for socioeconomic factors was a modest 1.12 but the PAF was 6.34%. The combined PAF of these three types of risk factors was 51.84%. Although the present analysis lacked data on some important risk factors for endometrial cancer, the results suggest that a large proportion of the etiology of endometrial cancer can be defined by known epidemiological risk factors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0959-8049
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2155-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Endometrial cancer: population attributable risks from reproductive, familial and socioeconomic factors.
pubmed:affiliation
Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany. K.Hemminki@dkfz.de
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't