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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1992-7-15
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pubmed:abstractText |
In this study a close correlation [correlation coefficient (r) = 0.86, P less than 0.001] was found between the blood lead level of 20 lead workers and their urinary excretion of lead for 24 h after intravenous infusion with 1 g of the chelating agent calcium disodium edetate. In addition, there were significant associations between lead levels in different bones (tibia/calcaneus: r = 0.93, P less than 0.001; tibia/phalanx: r = 0.67, P less than 0.002; calcaneus/phalanx: r = 0.80, P less than 0.001), as measured by in vivo X-ray fluorescence. Chelation produced no significant change in the lead level in either tibia or calcaneus. There was a significant correlation between chelated lead and bone lead (eg, for calcaneus, r = 0.62) in currently exposed workers. However, there was no significant relationship when a retired worker and an inactive worker were included (r = 0.14). It was concluded that chelatable lead mainly reflects the blood and soft-tissue lead pool, which is only partly dependent upon the skeletal lead content that comprises the biggest share of the total body burden.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0355-3140
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
113-9
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pubmed:dateRevised |
2010-8-25
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pubmed:meshHeading |
pubmed-meshheading:1604271-Adult,
pubmed-meshheading:1604271-Aged,
pubmed-meshheading:1604271-Bone and Bones,
pubmed-meshheading:1604271-Edetic Acid,
pubmed-meshheading:1604271-Humans,
pubmed-meshheading:1604271-Lead,
pubmed-meshheading:1604271-Lead Poisoning,
pubmed-meshheading:1604271-Male,
pubmed-meshheading:1604271-Microscopy, Fluorescence,
pubmed-meshheading:1604271-Middle Aged,
pubmed-meshheading:1604271-Occupational Diseases,
pubmed-meshheading:1604271-Occupational Exposure
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pubmed:year |
1992
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pubmed:articleTitle |
Chelated lead and bone lead.
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pubmed:affiliation |
Department of Occupational and Environmental Medicine, University Hospital, Lund, Sweden.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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