| pubmed-article:16041057 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16041057 | lifeskim:mentions | umls-concept:C0023290 | lld:lifeskim |
| pubmed-article:16041057 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
| pubmed-article:16041057 | lifeskim:mentions | umls-concept:C0042196 | lld:lifeskim |
| pubmed-article:16041057 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:16041057 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:16041057 | pubmed:dateCreated | 2005-7-25 | lld:pubmed |
| pubmed-article:16041057 | pubmed:abstractText | This study reports the efficacy of a heterologous prime-boost vaccination using DNA and vaccinia viruses (Western Reserve [WR] virus and modified [attenuated] vaccinia virus Ankara [MVA]) expressing the LACK antigen (Leishmania homologue of receptors for activated C kinase) and an intradermal murine infection model employing Leishmania infantum. At 1 month postinfection, vaccinated mice showed high levels of protection in the draining lymph node (240-fold reduction in parasite burden) coupled with significant levels of gamma interferon (20 to 200 ng/ml) and tumor necrosis factor alpha/lymphotoxin (8 to 134 pg/ml). Significant but lower levels of protection (6- to 30-fold) were observed in the spleen and liver. Comparable levels of protection were found for mice boosted with either LACK-WR or LACK-MVA, supporting the use of an attenuated vaccinia virus-based vaccine against human visceral leishmaniasis. | lld:pubmed |
| pubmed-article:16041057 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16041057 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16041057 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16041057 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16041057 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:16041057 | pubmed:issn | 0019-9567 | lld:pubmed |
| pubmed-article:16041057 | pubmed:author | pubmed-author:EstebanMarian... | lld:pubmed |
| pubmed-article:16041057 | pubmed:author | pubmed-author:Goldsmith-Pes... | lld:pubmed |
| pubmed-article:16041057 | pubmed:author | pubmed-author:McMahon-Pratt... | lld:pubmed |
| pubmed-article:16041057 | pubmed:author | pubmed-author:DondjiBlaiseB | lld:pubmed |
| pubmed-article:16041057 | pubmed:author | pubmed-author:Pérez-Jimenez... | lld:pubmed |
| pubmed-article:16041057 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16041057 | pubmed:volume | 73 | lld:pubmed |
| pubmed-article:16041057 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16041057 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16041057 | pubmed:pagination | 5286-9 | lld:pubmed |
| pubmed-article:16041057 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:16041057 | pubmed:meshHeading | pubmed-meshheading:16041057... | lld:pubmed |
| pubmed-article:16041057 | pubmed:meshHeading | pubmed-meshheading:16041057... | lld:pubmed |
| pubmed-article:16041057 | pubmed:meshHeading | pubmed-meshheading:16041057... | lld:pubmed |
| pubmed-article:16041057 | pubmed:meshHeading | pubmed-meshheading:16041057... | lld:pubmed |
| pubmed-article:16041057 | pubmed:meshHeading | pubmed-meshheading:16041057... | lld:pubmed |
| pubmed-article:16041057 | pubmed:meshHeading | pubmed-meshheading:16041057... | lld:pubmed |
| pubmed-article:16041057 | pubmed:meshHeading | pubmed-meshheading:16041057... | lld:pubmed |
| pubmed-article:16041057 | pubmed:meshHeading | pubmed-meshheading:16041057... | lld:pubmed |
| pubmed-article:16041057 | pubmed:meshHeading | pubmed-meshheading:16041057... | lld:pubmed |
| pubmed-article:16041057 | pubmed:meshHeading | pubmed-meshheading:16041057... | lld:pubmed |
| pubmed-article:16041057 | pubmed:meshHeading | pubmed-meshheading:16041057... | lld:pubmed |
| pubmed-article:16041057 | pubmed:meshHeading | pubmed-meshheading:16041057... | lld:pubmed |
| pubmed-article:16041057 | pubmed:meshHeading | pubmed-meshheading:16041057... | lld:pubmed |
| pubmed-article:16041057 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16041057 | pubmed:articleTitle | Heterologous prime-boost vaccination with the LACK antigen protects against murine visceral leishmaniasis. | lld:pubmed |
| pubmed-article:16041057 | pubmed:affiliation | Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520-8034, USA. | lld:pubmed |
| pubmed-article:16041057 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16041057 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:16041057 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:16041057 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16041057 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16041057 | lld:pubmed |
